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Blockade of the IL-1R1/TLR4 pathway mediates disease-modification therapeutic effects in a model of acquired epilepsy.
Iori, Valentina; Iyer, Anand M; Ravizza, Teresa; Beltrame, Luca; Paracchini, Lara; Marchini, Sergio; Cerovic, Milica; Hill, Cameron; Ferrari, Mariella; Zucchetti, Massimo; Molteni, Monica; Rossetti, Carlo; Brambilla, Riccardo; Steve White, H; D'Incalci, Maurizio; Aronica, Eleonora; Vezzani, Annamaria.
Afiliação
  • Iori V; Department of Neuroscience, IRCCS-Istituto di Ricerche Farmacologiche "Mario Negri", Milano, Italy; Department of (Neuro)Pathology, Academic Medical Center, Amsterdam, The Netherlands.
  • Iyer AM; Department of (Neuro)Pathology, Academic Medical Center, Amsterdam, The Netherlands.
  • Ravizza T; Department of Neuroscience, IRCCS-Istituto di Ricerche Farmacologiche "Mario Negri", Milano, Italy.
  • Beltrame L; Department of Oncology, IRCCS-Istituto di Ricerche Farmacologiche "Mario Negri", Milano, Italy.
  • Paracchini L; Department of Oncology, IRCCS-Istituto di Ricerche Farmacologiche "Mario Negri", Milano, Italy.
  • Marchini S; Department of Oncology, IRCCS-Istituto di Ricerche Farmacologiche "Mario Negri", Milano, Italy.
  • Cerovic M; Department of Neuroscience, IRCCS-Istituto di Ricerche Farmacologiche "Mario Negri", Milano, Italy.
  • Hill C; Department of Pharmacy, University of Washington, Seattle, WA, USA.
  • Ferrari M; Department of Oncology, IRCCS-Istituto di Ricerche Farmacologiche "Mario Negri", Milano, Italy.
  • Zucchetti M; Department of Oncology, IRCCS-Istituto di Ricerche Farmacologiche "Mario Negri", Milano, Italy.
  • Molteni M; Department of Biotechnologies and Life Sciences, Insubria University, Varese, Italy.
  • Rossetti C; Department of Biotechnologies and Life Sciences, Insubria University, Varese, Italy.
  • Brambilla R; Department of Neuroscience, IRCCS-Istituto di Ricerche Farmacologiche "Mario Negri", Milano, Italy; Neuroscience and Mental Health Research Institute, Division of Neuroscience, School of Biosciences, Cardiff University, United Kingdom.
  • Steve White H; Department of Pharmacy, University of Washington, Seattle, WA, USA.
  • D'Incalci M; Department of Oncology, IRCCS-Istituto di Ricerche Farmacologiche "Mario Negri", Milano, Italy.
  • Aronica E; Department of (Neuro)Pathology, Academic Medical Center, Amsterdam, The Netherlands; Swammerdam Institute for Life Sciences, Center for Neuroscience, University of Amsterdam, The Netherlands; Stichting Epilepsie Instellingen (SEIN) Nederland and Epilepsy Institute in The Netherlands Foundation, The
  • Vezzani A; Department of Neuroscience, IRCCS-Istituto di Ricerche Farmacologiche "Mario Negri", Milano, Italy. Electronic address: annamaria.vezzani@marionegri.it.
Neurobiol Dis ; 99: 12-23, 2017 Mar.
Article em En | MEDLINE | ID: mdl-27939857
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Anti-Inflamatórios não Esteroides / MicroRNAs / Epilepsia / Receptor 4 Toll-Like / Receptores Tipo I de Interleucina-1 / Anticonvulsivantes Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Neurobiol Dis Assunto da revista: NEUROLOGIA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Holanda
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Anti-Inflamatórios não Esteroides / MicroRNAs / Epilepsia / Receptor 4 Toll-Like / Receptores Tipo I de Interleucina-1 / Anticonvulsivantes Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Neurobiol Dis Assunto da revista: NEUROLOGIA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Holanda