[3 + 2] Cycloaddition of Oxazol-5-(4H)-ones with Nitrones for Diastereoselective Synthesis of Isoxazolidin-5-ones.

Zhao, Hong-Wu; Liu, Yue-Yang; Zhao, Yu-Di; Pang, Hai-Liang; Chen, Xiao-Qin; Song, Xiu-Qing; Tian, Ting; Li, Bo; Yang, Zhao; Du, Juan; Feng, Ning-Ning

Zhao, Hong-Wu; Liu, Yue-Yang; Zhao, Yu-Di; Pang, Hai-Liang; Chen, Xiao-Qin; Song, Xiu-Qing; Tian, Ting; Li, Bo; Yang, Zhao; Du, Juan; Feng, Ning-Ning.

Afiliação

Zhao HW; College of Life Science and Bio-engineering, Beijing University of Technology , No. 100 Pingleyuan, Chaoyang District, Beijing 100124, China.
Liu YY; College of Life Science and Bio-engineering, Beijing University of Technology , No. 100 Pingleyuan, Chaoyang District, Beijing 100124, China.
Zhao YD; College of Life Science and Bio-engineering, Beijing University of Technology , No. 100 Pingleyuan, Chaoyang District, Beijing 100124, China.
Pang HL; College of Life Science and Bio-engineering, Beijing University of Technology , No. 100 Pingleyuan, Chaoyang District, Beijing 100124, China.
Chen XQ; College of Life Science and Bio-engineering, Beijing University of Technology , No. 100 Pingleyuan, Chaoyang District, Beijing 100124, China.
Song XQ; College of Life Science and Bio-engineering, Beijing University of Technology , No. 100 Pingleyuan, Chaoyang District, Beijing 100124, China.
Tian T; College of Life Science and Bio-engineering, Beijing University of Technology , No. 100 Pingleyuan, Chaoyang District, Beijing 100124, China.
Li B; College of Life Science and Bio-engineering, Beijing University of Technology , No. 100 Pingleyuan, Chaoyang District, Beijing 100124, China.
Yang Z; College of Life Science and Bio-engineering, Beijing University of Technology , No. 100 Pingleyuan, Chaoyang District, Beijing 100124, China.
Du J; College of Life Science and Bio-engineering, Beijing University of Technology , No. 100 Pingleyuan, Chaoyang District, Beijing 100124, China.
Feng NN; College of Life Science and Bio-engineering, Beijing University of Technology , No. 100 Pingleyuan, Chaoyang District, Beijing 100124, China.

Org Lett ; 19(1): 26-29, 2017 01 06.

Article em En | MEDLINE | ID: mdl-27995798

ABSTRACT

ABSTRACT

In the presence of TMSCl, the [3 + 2] cycloaddition of oxazol-5-(4H)-ones with nitrones proceeded smoothly and furnished the desired isoxazolidin-5-ones with high diastereoselectivities in reasonable chemical yields. The chemical structure of the title compounds was firmly confirmed by X-ray single-crystal structure analysis.

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Org Lett Assunto da revista: BIOQUIMICA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: China

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