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The XBP1 Arm of the Unfolded Protein Response Induces Fibrogenic Activity in Hepatic Stellate Cells Through Autophagy.
Kim, Rosa S; Hasegawa, Daisuke; Goossens, Nicolas; Tsuchida, Takuma; Athwal, Varinder; Sun, Xiaochen; Robinson, Christopher L; Bhattacharya, Dipankar; Chou, Hsin-I; Zhang, David Y; Fuchs, Bryan C; Lee, Youngmin; Hoshida, Yujin; Friedman, Scott L.
Afiliação
  • Kim RS; Division of Liver Diseases, Department of Medicine, Liver Cancer Program, Tisch Cancer Institute, Graduate School of Biomedical Sciences, Icahn School of Medicine at Mount Sinai, New York, US.
  • Hasegawa D; Division of Liver Diseases, Department of Medicine, Liver Cancer Program, Tisch Cancer Institute, Graduate School of Biomedical Sciences, Icahn School of Medicine at Mount Sinai, New York, US.
  • Goossens N; Divisions of Gastroenterology and Hepatology, St. Marianna University School of Medicine, Kawasaki, Japan.
  • Tsuchida T; Division of Liver Diseases, Department of Medicine, Liver Cancer Program, Tisch Cancer Institute, Graduate School of Biomedical Sciences, Icahn School of Medicine at Mount Sinai, New York, US.
  • Athwal V; Divisions of Gastroenterology and Hepatology, Geneva University Hospital, Geneva, Switzerland.
  • Sun X; Division of Liver Diseases, Department of Medicine, Liver Cancer Program, Tisch Cancer Institute, Graduate School of Biomedical Sciences, Icahn School of Medicine at Mount Sinai, New York, US.
  • Robinson CL; Research Division, Mitsubishi Tanabe Pharma Corporation, Saitama, Japan.
  • Bhattacharya D; Division of Liver Diseases, Department of Medicine, Liver Cancer Program, Tisch Cancer Institute, Graduate School of Biomedical Sciences, Icahn School of Medicine at Mount Sinai, New York, US.
  • Chou HI; Institute of Human Development, University of Manchester, United Kingdom.
  • Zhang DY; Division of Liver Diseases, Department of Medicine, Liver Cancer Program, Tisch Cancer Institute, Graduate School of Biomedical Sciences, Icahn School of Medicine at Mount Sinai, New York, US.
  • Fuchs BC; Department of Surgery, Weill Cornell Medical College, New York, US.
  • Lee Y; Division of Liver Diseases, Department of Medicine, Liver Cancer Program, Tisch Cancer Institute, Graduate School of Biomedical Sciences, Icahn School of Medicine at Mount Sinai, New York, US.
  • Hoshida Y; Division of Liver Diseases, Department of Medicine, Liver Cancer Program, Tisch Cancer Institute, Graduate School of Biomedical Sciences, Icahn School of Medicine at Mount Sinai, New York, US.
  • Friedman SL; Division of Liver Diseases, Department of Medicine, Liver Cancer Program, Tisch Cancer Institute, Graduate School of Biomedical Sciences, Icahn School of Medicine at Mount Sinai, New York, US.
Sci Rep ; 6: 39342, 2016 12 20.
Article em En | MEDLINE | ID: mdl-27996033
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Autofagia / Células Estreladas do Fígado / Resposta a Proteínas não Dobradas / Hepatopatia Gordurosa não Alcoólica / Proteína 1 de Ligação a X-Box Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Sci Rep Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Autofagia / Células Estreladas do Fígado / Resposta a Proteínas não Dobradas / Hepatopatia Gordurosa não Alcoólica / Proteína 1 de Ligação a X-Box Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Sci Rep Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Estados Unidos