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Mutation G1629E Increases von Willebrand Factor Cleavage via a Cooperative Destabilization Mechanism.
Aponte-Santamaría, Camilo; Lippok, Svenja; Mittag, Judith J; Obser, Tobias; Schneppenheim, Reinhard; Baldauf, Carsten; Gräter, Frauke; Budde, Ulrich; Rädler, Joachim O.
Afiliação
  • Aponte-Santamaría C; Molecular Biomechanics Group, Heidelberg Institute for Theoretical Studies, Heidelberg, Germany; Interdisciplinary Center for Scientific Computing, Heidelberg University, Heidelberg, Germany. Electronic address: camilo.aponte@h-its.org.
  • Lippok S; Faculty of Physics and Center for NanoScience, Ludwig Maximilian University, Munich, Germany.
  • Mittag JJ; Faculty of Physics and Center for NanoScience, Ludwig Maximilian University, Munich, Germany.
  • Obser T; Department of Pediatric Hematology and Oncology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
  • Schneppenheim R; Department of Pediatric Hematology and Oncology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
  • Baldauf C; Theory Department, Fritz-Haber-Institut der Max-Planck-Gesellschaft, Berlin, Germany.
  • Gräter F; Molecular Biomechanics Group, Heidelberg Institute for Theoretical Studies, Heidelberg, Germany; Interdisciplinary Center for Scientific Computing, Heidelberg University, Heidelberg, Germany.
  • Budde U; Medilys Coagulation Laboratory, Asklepios Klinic Altona, Hamburg, Germany.
  • Rädler JO; Faculty of Physics and Center for NanoScience, Ludwig Maximilian University, Munich, Germany.
Biophys J ; 112(1): 57-65, 2017 Jan 10.
Article em En | MEDLINE | ID: mdl-28076816
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fator de von Willebrand / Simulação de Dinâmica Molecular / Proteólise / Mutação Limite: Humans Idioma: En Revista: Biophys J Ano de publicação: 2017 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fator de von Willebrand / Simulação de Dinâmica Molecular / Proteólise / Mutação Limite: Humans Idioma: En Revista: Biophys J Ano de publicação: 2017 Tipo de documento: Article