Arterial Stiffness in Aortic Stenosis: Relationship with Severity and Echocardiographic Procedures Response.
High Blood Press Cardiovasc Prev
; 24(1): 19-27, 2017 Mar.
Article
em En
| MEDLINE
| ID: mdl-28078606
ABSTRACT
INTRODUCTION:
Aortic stenosis (AS) is more than only a degenerative disease, it could be also an atherosclerotic-like process involving the valve instead of the vessels. Little is known about the relation of arterial stiffness and AS.AIM:
We sought to determine wether pulse wave velocity (PWV), is related to AS severity and to the procedures response, both as surgical aortic-valve-replacement (AVR) and trascatheter-aortic-valve-implantation (TAVI).METHODS:
30 patients with severe AS were treated (15 AVR, 15 TAVI). Before the procedures (t0) and after 1 week (t1) echocardiography and PWV were evaluated.RESULTS:
On the whole population, subjects with higher PWV showed higher transvalvular pressure gradient at baseline (mean 56.5 ± 15.1 vs 45.4 ± 9.5; peak 93.3 ± 26.4 vs 73.3 ± 14.9, p = 0.02) and, a significantly greater response to the procedures (mean -42.9 ± 17.2 vs -27.9 ± 10.1, peak -68.7 ± 29.2 vs -42.8 ± 16.4, p = 0.02). When the two different procedures groups were separated, data were confirmed only in the TAVI subgroup.CONCLUSIONS:
In patients undergoing procedures for AS, PWV is correlated with transvalvular gradient and, in TAVI subjects, is able to predict the echocardiographic response. Baseline evaluation of PWV in patients candidates to TAVI can help the selection of subjects, even if larger and longer studies are needed before definitive conclusion can be drawn.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Aorta
/
Valva Aórtica
/
Estenose da Valva Aórtica
/
Ecocardiografia Doppler
/
Rigidez Vascular
/
Análise de Onda de Pulso
/
Hemodinâmica
Tipo de estudo:
Prognostic_studies
Limite:
Aged
/
Aged80
/
Female
/
Humans
/
Male
Idioma:
En
Revista:
High Blood Press Cardiovasc Prev
Ano de publicação:
2017
Tipo de documento:
Article
País de afiliação:
Itália