Benzyl isothiocyanate induces protective autophagy in human lung cancer cells through an endoplasmic reticulum stress-mediated mechanism.

Zhang, Qi-Cheng; Pan, Zhen-Hua; Liu, Bo-Ning; Meng, Zhao-Wei; Wu, Xiang; Zhou, Qing-Hua; Xu, Ke

Zhang, Qi-Cheng; Pan, Zhen-Hua; Liu, Bo-Ning; Meng, Zhao-Wei; Wu, Xiang; Zhou, Qing-Hua; Xu, Ke.

Afiliação

Zhang QC; Tianjin Key Laboratory of Lung Cancer Metastasis and Tumor Microenvironment, Tianjin Lung Cancer Institute, Tianjin Medical University General Hospital, Tianjin 300052, China.
Pan ZH; Tianjin Key Laboratory of Lung Cancer Metastasis and Tumor Microenvironment, Tianjin Lung Cancer Institute, Tianjin Medical University General Hospital, Tianjin 300052, China.
Liu BN; Tianjin Key Laboratory of Lung Cancer Metastasis and Tumor Microenvironment, Tianjin Lung Cancer Institute, Tianjin Medical University General Hospital, Tianjin 300052, China.
Meng ZW; Department of Nuclear Medicine, Tianjin Medical University General Hospital, Tianjin 300052, China.
Wu X; Core Facility Center, Tianjin Medical University General Hospital, Tianjin 300052, China.
Zhou QH; Tianjin Key Laboratory of Lung Cancer Metastasis and Tumor Microenvironment, Tianjin Lung Cancer Institute, Tianjin Medical University General Hospital, Tianjin 300052, China.
Xu K; Tianjin Key Laboratory of Lung Cancer Metastasis and Tumor Microenvironment, Tianjin Lung Cancer Institute, Tianjin Medical University General Hospital, Tianjin 300052, China.

Acta Pharmacol Sin ; 38(4): 539-550, 2017 Apr.

Article em En | MEDLINE | ID: mdl-28112178

Assuntos

Autofagia/efeitos dos fármacos; Estresse do Retículo Endoplasmático/efeitos dos fármacos; Isotiocianatos/uso terapêutico; Neoplasias Pulmonares/tratamento farmacológico; Adenina/análogos & derivados; Adenina/farmacologia; Animais; Proteína 5 Relacionada à Autofagia/metabolismo; Linhagem Celular Tumoral; Feminino; Xenoenxertos; Humanos; Neoplasias Pulmonares/metabolismo; Neoplasias Pulmonares/patologia; Camundongos Endogâmicos BALB C; Proteínas Associadas aos Microtúbulos/metabolismo; Transplante de Neoplasias; Fenilbutiratos/farmacologia

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Autofagia / Isotiocianatos / Estresse do Retículo Endoplasmático / Neoplasias Pulmonares Limite: Animals / Female / Humans Idioma: En Revista: Acta Pharmacol Sin Assunto da revista: FARMACOLOGIA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: China

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