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MLL-AF9 and MLL-AF4 oncofusion proteins bind a distinct enhancer repertoire and target the RUNX1 program in 11q23 acute myeloid leukemia.
Prange, K H M; Mandoli, A; Kuznetsova, T; Wang, S-Y; Sotoca, A M; Marneth, A E; van der Reijden, B A; Stunnenberg, H G; Martens, J H A.
Afiliação
  • Prange KHM; Department of Molecular Biology, Faculty of Science, Radboud Institute for Molecular Life Sciences, Radboud University, Nijmegen, The Netherlands.
  • Mandoli A; Department of Molecular Biology, Faculty of Science, Radboud Institute for Molecular Life Sciences, Radboud University, Nijmegen, The Netherlands.
  • Kuznetsova T; Department of Molecular Biology, Faculty of Science, Radboud Institute for Molecular Life Sciences, Radboud University, Nijmegen, The Netherlands.
  • Wang SY; Department of Molecular Biology, Faculty of Science, Radboud Institute for Molecular Life Sciences, Radboud University, Nijmegen, The Netherlands.
  • Sotoca AM; Department of Molecular Biology, Faculty of Science, Radboud Institute for Molecular Life Sciences, Radboud University, Nijmegen, The Netherlands.
  • Marneth AE; Laboratory of Hematology, Department of Laboratory Medicine, Radboud University Medical Center, Nijmegen, The Netherlands.
  • van der Reijden BA; Laboratory of Hematology, Department of Laboratory Medicine, Radboud University Medical Center, Nijmegen, The Netherlands.
  • Stunnenberg HG; Department of Molecular Biology, Faculty of Science, Radboud Institute for Molecular Life Sciences, Radboud University, Nijmegen, The Netherlands.
  • Martens JHA; Department of Molecular Biology, Faculty of Science, Radboud Institute for Molecular Life Sciences, Radboud University, Nijmegen, The Netherlands.
Oncogene ; 36(23): 3346-3356, 2017 06 08.
Article em En | MEDLINE | ID: mdl-28114278

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Cromossomos Humanos Par 11 / Leucemia Mieloide Aguda / Regulação Neoplásica da Expressão Gênica / Proteínas de Fusão Oncogênica / Elementos Facilitadores Genéticos / Proteína de Leucina Linfoide-Mieloide / Subunidade alfa 2 de Fator de Ligação ao Core Tipo de estudo: Prognostic_studies Limite: Adult / Female / Humans / Infant / Male / Middle aged Idioma: En Revista: Oncogene Assunto da revista: BIOLOGIA MOLECULAR / NEOPLASIAS Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Holanda

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Cromossomos Humanos Par 11 / Leucemia Mieloide Aguda / Regulação Neoplásica da Expressão Gênica / Proteínas de Fusão Oncogênica / Elementos Facilitadores Genéticos / Proteína de Leucina Linfoide-Mieloide / Subunidade alfa 2 de Fator de Ligação ao Core Tipo de estudo: Prognostic_studies Limite: Adult / Female / Humans / Infant / Male / Middle aged Idioma: En Revista: Oncogene Assunto da revista: BIOLOGIA MOLECULAR / NEOPLASIAS Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Holanda