BrachyView: Combining LDR seed positions with transrectal ultrasound imaging in a prostate gel phantom.
Phys Med
; 34: 55-64, 2017 Feb.
Article
em En
| MEDLINE
| ID: mdl-28118951
ABSTRACT
PURPOSE:
BrachyView is a novel in-body imaging system which aims to provide LDR brachytherapy seeds position reconstruction within the prostate in real-time. The first prototype is presented in this study the probe consists of a gamma camera featuring three single cone pinhole collimators embedded in a tungsten tube, above three, high resolution pixelated detectors (Timepix).METHODS:
The prostate was imaged with a TRUS system using a sagittal crystal with a 2.5mm slice thickness. Eleven needles containing a total of thirty 0.508U125I seeds were implanted under ultrasound guidance. A CT scan was used to localise the seed positions, as well as provide a reference when performing the image co-registration between the BrachyView coordinate system and the TRUS coordinate system. An in-house visualisation software interface was developed to provide a quantitative 3D reconstructed prostate based on the TRUS images and co-registered with the LDR seeds in situ. A rigid body image registration was performed between the BrachyView and TRUS systems, with the BrachyView and CT-derived source locations compared.RESULTS:
The reconstructed seed positions determined by the BrachyView probe showed a maximum discrepancy of 1.78mm, with 75% of the seeds reconstructed within 1mm of their nominal location. An accurate co-registration between the BrachyView and TRUS coordinate system was established.CONCLUSIONS:
The BrachyView system has shown its ability to reconstruct all implanted LDR seeds within a tissue equivalent prostate gel phantom, providing both anatomical and seed position information in a single interface.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Próstata
/
Doses de Radiação
/
Reto
/
Braquiterapia
/
Ultrassonografia
/
Imagens de Fantasmas
/
Radioterapia Guiada por Imagem
Tipo de estudo:
Diagnostic_studies
Limite:
Humans
/
Male
Idioma:
En
Revista:
Phys Med
Assunto da revista:
BIOFISICA
/
BIOLOGIA
/
MEDICINA
Ano de publicação:
2017
Tipo de documento:
Article