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The integrin PSI domain has an endogenous thiol isomerase function and is a novel target for antiplatelet therapy.
Zhu, Guangheng; Zhang, Qing; Reddy, Emily C; Carrim, Naadiya; Chen, Yunfeng; Xu, Xiaohong Ruby; Xu, Miao; Wang, Yiming; Hou, Yan; Ma, Li; Li, Yan; Rui, Min; Petruzziello-Pellegrini, Tania N; Lavalle, Christopher; Stratton, Tyler W; Lei, Xi; Adili, Reheman; Chen, Pingguo; Zhu, Cheng; Wilkins, John A; Hynes, Richard O; Freedman, John; Ni, Heyu.
Afiliação
  • Zhu G; Toronto Platelet Immunobiology Group and Department of Laboratory Medicine, Keenan Research Centre for Biomedical Science, St. Michael's Hospital, University of Toronto, Toronto, ON, Canada.
  • Zhang Q; Toronto Platelet Immunobiology Group and Department of Laboratory Medicine, Keenan Research Centre for Biomedical Science, St. Michael's Hospital, University of Toronto, Toronto, ON, Canada.
  • Reddy EC; Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, Guangzhou, Guangdong, China.
  • Carrim N; Institute of Sun Yat-sen University in Shenzhen, Shenzhen, Guangdong, China.
  • Chen Y; Toronto Platelet Immunobiology Group and Department of Laboratory Medicine, Keenan Research Centre for Biomedical Science, St. Michael's Hospital, University of Toronto, Toronto, ON, Canada.
  • Xu XR; Toronto Platelet Immunobiology Group and Department of Laboratory Medicine, Keenan Research Centre for Biomedical Science, St. Michael's Hospital, University of Toronto, Toronto, ON, Canada.
  • Xu M; Canadian Blood Services, Toronto, ON, Canada.
  • Wang Y; Department of Physiology, and.
  • Hou Y; Toronto Platelet Immunobiology Group and Department of Laboratory Medicine, Keenan Research Centre for Biomedical Science, St. Michael's Hospital, University of Toronto, Toronto, ON, Canada.
  • Ma L; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada.
  • Li Y; Toronto Platelet Immunobiology Group and Department of Laboratory Medicine, Keenan Research Centre for Biomedical Science, St. Michael's Hospital, University of Toronto, Toronto, ON, Canada.
  • Rui M; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada.
  • Petruzziello-Pellegrini TN; Toronto Platelet Immunobiology Group and Department of Laboratory Medicine, Keenan Research Centre for Biomedical Science, St. Michael's Hospital, University of Toronto, Toronto, ON, Canada.
  • Lavalle C; Canadian Blood Services, Toronto, ON, Canada.
  • Stratton TW; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada.
  • Lei X; Toronto Platelet Immunobiology Group and Department of Laboratory Medicine, Keenan Research Centre for Biomedical Science, St. Michael's Hospital, University of Toronto, Toronto, ON, Canada.
  • Adili R; Toronto Platelet Immunobiology Group and Department of Laboratory Medicine, Keenan Research Centre for Biomedical Science, St. Michael's Hospital, University of Toronto, Toronto, ON, Canada.
  • Chen P; Canadian Blood Services, Toronto, ON, Canada.
  • Zhu C; Toronto Platelet Immunobiology Group and Department of Laboratory Medicine, Keenan Research Centre for Biomedical Science, St. Michael's Hospital, University of Toronto, Toronto, ON, Canada.
  • Wilkins JA; Canadian Blood Services, Toronto, ON, Canada.
  • Hynes RO; Toronto Platelet Immunobiology Group and Department of Laboratory Medicine, Keenan Research Centre for Biomedical Science, St. Michael's Hospital, University of Toronto, Toronto, ON, Canada.
  • Freedman J; Canadian Blood Services, Toronto, ON, Canada.
  • Ni H; Toronto Platelet Immunobiology Group and Department of Laboratory Medicine, Keenan Research Centre for Biomedical Science, St. Michael's Hospital, University of Toronto, Toronto, ON, Canada.
Blood ; 129(13): 1840-1854, 2017 03 30.
Article em En | MEDLINE | ID: mdl-28122739
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Isomerases de Dissulfetos de Proteínas / Cadeias beta de Integrinas Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Blood Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Canadá
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Isomerases de Dissulfetos de Proteínas / Cadeias beta de Integrinas Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Blood Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Canadá