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Admixture mapping in two Mexican samples identifies significant associations of locus ancestry with triglyceride levels in the BUD13/ZNF259/APOA5 region and fine mapping points to rs964184 as the main driver of the association signal.
Parra, Esteban J; Mazurek, Andrew; Gignoux, Christopher R; Sockell, Alexandra; Agostino, Michael; Morris, Andrew P; Petty, Lauren E; Hanis, Craig L; Cox, Nancy J; Valladares-Salgado, Adan; Below, Jennifer E; Cruz, Miguel.
Afiliação
  • Parra EJ; Department of Anthropology, University of Toronto at Mississauga, Mississauga, ON, Canada.
  • Mazurek A; Department of Anthropology, University of Toronto at Mississauga, Mississauga, ON, Canada.
  • Gignoux CR; Department of Genetics, Stanford University, Stanford, CA, United States of America.
  • Sockell A; School of Medicine, Stanford University, Stanford, CA, United States of America.
  • Agostino M; Department of Anthropology, University of Toronto at Mississauga, Mississauga, ON, Canada.
  • Morris AP; Department of Biostatistics, University of Liverpool, Liverpool, United Kingdom.
  • Petty LE; Department of Epidemiology, Human Genetics & Environmental Sciences, University of Texas School of Public Health, Houston, TX, United States of America.
  • Hanis CL; Department of Epidemiology, Human Genetics & Environmental Sciences, University of Texas School of Public Health, Houston, TX, United States of America.
  • Cox NJ; Division of Genetic Medicine, Department of Medicine, Vanderbilt University, Nashville, TN, United States of America.
  • Valladares-Salgado A; Unidad de Investigación Médica en Bioquímica, Hospital de Especialidades, Centro Médico Nacional Siglo XXI, IMSS, Mexico City, Mexico.
  • Below JE; Department of Epidemiology, Human Genetics & Environmental Sciences, University of Texas School of Public Health, Houston, TX, United States of America.
  • Cruz M; Unidad de Investigación Médica en Bioquímica, Hospital de Especialidades, Centro Médico Nacional Siglo XXI, IMSS, Mexico City, Mexico.
PLoS One ; 12(2): e0172880, 2017.
Article em En | MEDLINE | ID: mdl-28245265
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Triglicerídeos / Proteínas de Transporte / Proteínas de Ligação a RNA / Apolipoproteína A-V Tipo de estudo: Risk_factors_studies Limite: Adult / Female / Humans / Male / Middle aged País/Região como assunto: Mexico Idioma: En Revista: PLoS One Assunto da revista: CIENCIA / MEDICINA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Canadá
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Triglicerídeos / Proteínas de Transporte / Proteínas de Ligação a RNA / Apolipoproteína A-V Tipo de estudo: Risk_factors_studies Limite: Adult / Female / Humans / Male / Middle aged País/Região como assunto: Mexico Idioma: En Revista: PLoS One Assunto da revista: CIENCIA / MEDICINA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Canadá