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The molecular biology of pelvi-ureteric junction obstruction.
Jackson, Laura; Woodward, Mark; Coward, Richard J.
Afiliação
  • Jackson L; Bristol Renal Group, University of Bristol, Dorothy Hodgkin Building, Whitson Street, Bristol, BS1 3NY, UK. laura.jackson@bristol.ac.uk.
  • Woodward M; Bristol Royal Hospital for Children, Bristol, UK. laura.jackson@bristol.ac.uk.
  • Coward RJ; Bristol Royal Hospital for Children, Bristol, UK.
Pediatr Nephrol ; 33(4): 553-571, 2018 04.
Article em En | MEDLINE | ID: mdl-28286898
ABSTRACT
Over recent years routine ultrasound scanning has identified increasing numbers of neonates as having hydronephrosis and pelvi-ureteric junction obstruction (PUJO). This patient group presents a diagnostic and management challenge for paediatric nephrologists and urologists. In this review we consider the known molecular mechanisms underpinning PUJO and review the potential of utilising this information to develop novel therapeutics and diagnostic biomarkers to improve the care of children with this disorder.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Obstrução Ureteral / Biomarcadores / Rim Displásico Multicístico / Hidronefrose Limite: Animals / Humans Idioma: En Revista: Pediatr Nephrol Assunto da revista: NEFROLOGIA / PEDIATRIA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Reino Unido
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Obstrução Ureteral / Biomarcadores / Rim Displásico Multicístico / Hidronefrose Limite: Animals / Humans Idioma: En Revista: Pediatr Nephrol Assunto da revista: NEFROLOGIA / PEDIATRIA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Reino Unido