Improved Discrimination of Myocardial Perfusion Defects at Low Energy Levels Using Virtual Monochromatic Imaging.
J Comput Assist Tomogr
; 41(4): 661-667, 2017.
Article
em En
| MEDLINE
| ID: mdl-28296684
ABSTRACT
OBJECTIVES:
The aim of this study was to explore the diagnostic performance of dual-energy computed tomography perfusion (DE-CTP) at different energy levels.METHODS:
Patients with known or suspected coronary artery disease underwent stress and rest DE-CTP and single-photon emission computed tomography. Images were evaluated using monochromatic data, and perfusion defects were initially identified in a qualitative manner and subsequently confirmed using attenuation levels.RESULTS:
Thirty-six patients were included. Sensitivity, specificity, positive predictive value, and negative predictive value of DE-CTP for the identification of perfusion defects were 84.1%, 94.2%, 77.3%, and 96.2%, respectively. Perfusion defects showed significantly lower attenuation than normal segments, with the largest differences among low energy levels (sensitivity of 96% and specificity of 98% using a cutoff value ≤ 153 Hounsfield units at 40 keV), progressively declining at the higher levels (P < 0.001).CONCLUSIONS:
Dual-energy CTP at the lowest energy levels allowed improved discrimination of perfusion defects compared with higher energy levels.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Doença da Artéria Coronariana
/
Tomografia Computadorizada de Emissão de Fóton Único
/
Angiografia Coronária
/
Imagem de Perfusão do Miocárdio
/
Angiografia por Tomografia Computadorizada
Tipo de estudo:
Diagnostic_studies
/
Observational_studies
/
Prognostic_studies
/
Qualitative_research
Limite:
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
J Comput Assist Tomogr
Ano de publicação:
2017
Tipo de documento:
Article
País de afiliação:
Argentina