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Large scale genomic analysis shows no evidence for pathogen adaptation between the blood and cerebrospinal fluid niches during bacterial meningitis.
Lees, John A; Kremer, Philip H C; Manso, Ana S; Croucher, Nicholas J; Ferwerda, Bart; Serón, Mercedes Valls; Oggioni, Marco R; Parkhill, Julian; Brouwer, Matthijs C; van der Ende, Arie; van de Beek, Diederik; Bentley, Stephen D.
Afiliação
  • Lees JA; 1​Pathogen Genomics, Wellcome Trust Sanger Institute, Hinxton, UK.
  • Kremer PHC; 2​Department of Neurology, Center for Infection and Immunity Amsterdam (CINIMA), Academic Medical Center, Amsterdam, The Netherlands.
  • Manso AS; 3​Department of Genetics, University of Leicester, Leicester, UK.
  • Croucher NJ; 4​Department of Infectious Disease Epidemiology, Imperial College London, London, UK.
  • Ferwerda B; 2​Department of Neurology, Center for Infection and Immunity Amsterdam (CINIMA), Academic Medical Center, Amsterdam, The Netherlands.
  • Serón MV; 2​Department of Neurology, Center for Infection and Immunity Amsterdam (CINIMA), Academic Medical Center, Amsterdam, The Netherlands.
  • Oggioni MR; 3​Department of Genetics, University of Leicester, Leicester, UK.
  • Parkhill J; 1​Pathogen Genomics, Wellcome Trust Sanger Institute, Hinxton, UK.
  • Brouwer MC; 2​Department of Neurology, Center for Infection and Immunity Amsterdam (CINIMA), Academic Medical Center, Amsterdam, The Netherlands.
  • van der Ende A; 5​Department of Medical Microbiology, Center for Infection and Immunity Amsterdam (CINIMA), Academic Medical Center, Amsterdam, The Netherlands.
  • van de Beek D; 6​Netherlands Reference Laboratory for Bacterial Meningitis, Academic Medical Center, Amsterdam, The Netherlands.
  • Bentley SD; 2​Department of Neurology, Center for Infection and Immunity Amsterdam (CINIMA), Academic Medical Center, Amsterdam, The Netherlands.
Microb Genom ; 3(1): e000103, 2017 01.
Article em En | MEDLINE | ID: mdl-28348877

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Streptococcus pneumoniae / Adaptação Biológica / Barreira Hematoencefálica / Meningite Meningocócica / Meningite Pneumocócica / Neisseria meningitidis Limite: Humans Idioma: En Revista: Microb Genom Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Reino Unido

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Streptococcus pneumoniae / Adaptação Biológica / Barreira Hematoencefálica / Meningite Meningocócica / Meningite Pneumocócica / Neisseria meningitidis Limite: Humans Idioma: En Revista: Microb Genom Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Reino Unido