Muscle-specific expression of the RNA-binding protein Staufen1 induces progressive skeletal muscle atrophy via regulation of phosphatase tensin homolog.

Crawford Parks, Tara E; Ravel-Chapuis, Aymeric; Bondy-Chorney, Emma; Renaud, Jean-Marc; Côté, Jocelyn; Jasmin, Bernard J

Crawford Parks, Tara E; Ravel-Chapuis, Aymeric; Bondy-Chorney, Emma; Renaud, Jean-Marc; Côté, Jocelyn; Jasmin, Bernard J.

Afiliação

Crawford Parks TE; Department of Cellular and Molecular Medicine, Centre for Neuromuscular Disease, Faculty of Medicine, University of Ottawa, Ottawa, ON K1H 8M5, Canada.
Ravel-Chapuis A; Department of Cellular and Molecular Medicine, Centre for Neuromuscular Disease, Faculty of Medicine, University of Ottawa, Ottawa, ON K1H 8M5, Canada.
Bondy-Chorney E; Department of Cellular and Molecular Medicine, Centre for Neuromuscular Disease, Faculty of Medicine, University of Ottawa, Ottawa, ON K1H 8M5, Canada.
Renaud JM; Department of Cellular and Molecular Medicine, Centre for Neuromuscular Disease, Faculty of Medicine, University of Ottawa, Ottawa, ON K1H 8M5, Canada.
Côté J; Department of Cellular and Molecular Medicine, Centre for Neuromuscular Disease, Faculty of Medicine, University of Ottawa, Ottawa, ON K1H 8M5, Canada.
Jasmin BJ; Department of Cellular and Molecular Medicine, Centre for Neuromuscular Disease, Faculty of Medicine, University of Ottawa, Ottawa, ON K1H 8M5, Canada.

Hum Mol Genet ; 26(10): 1821-1838, 2017 05 15.

Article em En | MEDLINE | ID: mdl-28369467

Assuntos

Proteínas de Ligação a RNA/genética; Proteínas de Ligação a RNA/metabolismo; Esclerose Lateral Amiotrófica/metabolismo; Animais; Expressão Gênica; Camundongos; Camundongos Knockout; Denervação Muscular; Músculo Esquelético/metabolismo; Músculos/metabolismo; Atrofia Muscular/metabolismo; Atrofia Muscular Espinal/metabolismo; Distrofia Miotônica/metabolismo; PTEN Fosfo-Hidrolase/genética; PTEN Fosfo-Hidrolase/metabolismo; Fosfatidilinositol 3-Quinases/genética; RNA/metabolismo; Processamento Pós-Transcricional do RNA; Transdução de Sinais; Tensinas

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas de Ligação a RNA Limite: Animals Idioma: En Revista: Hum Mol Genet Assunto da revista: BIOLOGIA MOLECULAR / GENETICA MEDICA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Canadá

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