Ionic liquids based on imidazole for online concentration of catecholamines in capillary electrophoresis.
J Sep Sci
; 40(10): 2304-2311, 2017 May.
Article
em En
| MEDLINE
| ID: mdl-28371456
ABSTRACT
Potential possibilities of long-chain ionic liquids based on imidazole (1-dodecyl-3-methylimidazolium chloride and 1-cetyl-3-methylimidazolium chloride) for online sample concentration techniques (field-amplified sample stacking, head-column field-amplified sample stacking, and sweeping) of catecholamines were studied in both capillary zone electrophoresis and micellar electrokinetic chromatography. The use of a high-conductivity sample matrix in sweeping was found to significantly increase the separation efficiency of analyte up to 2 × 106 theoretical plates per meter and remarkably reduce limits of detection for catecholamines up to 50 ng/mL. This approach was shown to be suitable for the determination of trace amounts of catecholamines in biological fluids.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Catecolaminas
/
Líquidos Iônicos
/
Imidazóis
Idioma:
En
Revista:
J Sep Sci
Ano de publicação:
2017
Tipo de documento:
Article
País de afiliação:
Federação Russa