Heat shock protein 104 (Hsp104)-mediated curing of [PSI+] yeast prions depends on both [PSI+] conformation and the properties of the Hsp104 homologs.

Zhao, Xiaohong; Rodriguez, Ramon; Silberman, Rebecca E; Ahearn, Joseph M; Saidha, Sheela; Cummins, Kaelyn C; Eisenberg, Evan; Greene, Lois E

Heat shock protein 104 (Hsp104)-mediated curing of [PSI⁺] yeast prions depends on both [PSI⁺] conformation and the properties of the Hsp104 homologs.

Zhao, Xiaohong; Rodriguez, Ramon; Silberman, Rebecca E; Ahearn, Joseph M; Saidha, Sheela; Cummins, Kaelyn C; Eisenberg, Evan; Greene, Lois E.

Afiliação

Zhao X; From the Laboratory of Cell Biology, NHLBI, National Institutes of Health, Bethesda, Maryland 20892-0301.
Rodriguez R; From the Laboratory of Cell Biology, NHLBI, National Institutes of Health, Bethesda, Maryland 20892-0301.
Silberman RE; From the Laboratory of Cell Biology, NHLBI, National Institutes of Health, Bethesda, Maryland 20892-0301.
Ahearn JM; From the Laboratory of Cell Biology, NHLBI, National Institutes of Health, Bethesda, Maryland 20892-0301.
Saidha S; From the Laboratory of Cell Biology, NHLBI, National Institutes of Health, Bethesda, Maryland 20892-0301.
Cummins KC; From the Laboratory of Cell Biology, NHLBI, National Institutes of Health, Bethesda, Maryland 20892-0301.
Eisenberg E; From the Laboratory of Cell Biology, NHLBI, National Institutes of Health, Bethesda, Maryland 20892-0301.
Greene LE; From the Laboratory of Cell Biology, NHLBI, National Institutes of Health, Bethesda, Maryland 20892-0301 greenel@helix.nih.gov.

J Biol Chem ; 292(21): 8630-8641, 2017 05 26.

Article em En | MEDLINE | ID: mdl-28373280

Assuntos

Proteínas de Choque Térmico/metabolismo; Fatores de Terminação de Peptídeos/metabolismo; Príons/metabolismo; Proteínas de Saccharomyces cerevisiae/metabolismo; Saccharomyces cerevisiae/metabolismo; Adenosina Trifosfatases/genética; Adenosina Trifosfatases/metabolismo; Candida albicans/genética; Candida albicans/metabolismo; Teste de Complementação Genética; Proteínas de Choque Térmico/genética; Fatores de Terminação de Peptídeos/genética; Príons/genética; Conformação Proteica; Saccharomyces cerevisiae/genética; Proteínas de Saccharomyces cerevisiae/genética; Schizosaccharomyces/genética; Schizosaccharomyces/metabolismo

Palavras-chave

Hsp104; amyloid; molecular chaperone; prion; protein folding; yeast

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Saccharomyces cerevisiae / Príons / Fatores de Terminação de Peptídeos / Proteínas de Saccharomyces cerevisiae / Proteínas de Choque Térmico Idioma: En Revista: J Biol Chem Ano de publicação: 2017 Tipo de documento: Article

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