Baseline JAK phosphorylation profile of peripheral blood leukocytes, studied by whole blood phosphospecific flow cytometry, is associated with 1-year treatment response in early rheumatoid arthritis.

Kuuliala, Krista; Kuuliala, Antti; Koivuniemi, Riitta; Kautiainen, Hannu; Repo, Heikki; Leirisalo-Repo, Marjatta

Kuuliala, Krista; Kuuliala, Antti; Koivuniemi, Riitta; Kautiainen, Hannu; Repo, Heikki; Leirisalo-Repo, Marjatta.

Afiliação

Kuuliala K; Bacteriology and Immunology, Helsinki University Hospital and University of Helsinki, Helsinki, Finland. krista.kuuliala@helsinki.fi.
Kuuliala A; Bacteriology and Immunology, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.
Koivuniemi R; Rheumatology, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.
Kautiainen H; Primary Health Care, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.
Repo H; General Practice, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.
Leirisalo-Repo M; Unit of Primary Health Care, Kuopio University Hospital, Kuopio, Finland.

Arthritis Res Ther ; 19(1): 75, 2017 04 11.

Article em En | MEDLINE | ID: mdl-28399940

Assuntos

Antirreumáticos/uso terapêutico; Artrite Reumatoide/tratamento farmacológico; Artrite Reumatoide/metabolismo; Biomarcadores/sangue; Janus Quinases/metabolismo; Idoso; Feminino; Citometria de Fluxo; Humanos; Linfócitos/metabolismo; Masculino; Pessoa de Meia-Idade; Monócitos/metabolismo; Fosforilação

Palavras-chave

Biomarker; Blood; Disease-modifying antirheumatic drug; Janus kinases; Leukocyte; Phosphorylation; Rheumatoid arthritis

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Artrite Reumatoide / Biomarcadores / Antirreumáticos / Janus Quinases Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Arthritis Res Ther Assunto da revista: REUMATOLOGIA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Finlândia

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