Novel bioactive molecules from Lentzea violacea strain AS 08 using one strain-many compounds (OSMAC) approach.

Hussain, Aehtesham; Rather, Muzafar A; Dar, Mohd S; Aga, Mushtaq A; Ahmad, Nisar; Manzoor, Aabid; Qayum, Arem; Shah, Aiyatullah; Mushtaq, Saleem; Ahmad, Zahoor; Hassan, Qazi P

Hussain, Aehtesham; Rather, Muzafar A; Dar, Mohd S; Aga, Mushtaq A; Ahmad, Nisar; Manzoor, Aabid; Qayum, Arem; Shah, Aiyatullah; Mushtaq, Saleem; Ahmad, Zahoor; Hassan, Qazi P.

Afiliação

Hussain A; Microbial Biotechnology Division, CSIR - Indian Institute of Integrative Medicine, Sanatnagar, Srinagar, Jammu & Kashmir 190005, India; Academy of Scientific and Innovative Research, CSIR - Indian Institute of Integrative Medicine, Canal Road, Jammu Tawi, 180001, India.
Rather MA; Clinical Microbiology and PK/PD Division, CSIR - Indian Institute of Integrative Medicine, Sanatnagar, Srinagar, Jammu & Kashmir 190005, India.
Dar MS; Cancer Pharmacology Division, CSIR - Indian Institute of Integrative Medicine, Jammu Tawi, 180001, India.
Aga MA; Medicinal Chemistry Division, CSIR - Indian Institute of Integrative Medicine, Sanatnagar, Srinagar, Jammu & Kashmir 190005, India.
Ahmad N; Medicinal Chemistry Division, CSIR - Indian Institute of Integrative Medicine, Sanatnagar, Srinagar, Jammu & Kashmir 190005, India.
Manzoor A; Microbial Biotechnology Division, CSIR - Indian Institute of Integrative Medicine, Sanatnagar, Srinagar, Jammu & Kashmir 190005, India.
Qayum A; Cancer Pharmacology Division, CSIR - Indian Institute of Integrative Medicine, Jammu Tawi, 180001, India.
Shah A; Microbial Biotechnology Division, CSIR - Indian Institute of Integrative Medicine, Sanatnagar, Srinagar, Jammu & Kashmir 190005, India.
Mushtaq S; Microbial Biotechnology Division, CSIR - Indian Institute of Integrative Medicine, Sanatnagar, Srinagar, Jammu & Kashmir 190005, India.
Ahmad Z; Clinical Microbiology and PK/PD Division, CSIR - Indian Institute of Integrative Medicine, Sanatnagar, Srinagar, Jammu & Kashmir 190005, India.
Hassan QP; Microbial Biotechnology Division, CSIR - Indian Institute of Integrative Medicine, Sanatnagar, Srinagar, Jammu & Kashmir 190005, India; Academy of Scientific and Innovative Research, CSIR - Indian Institute of Integrative Medicine, Canal Road, Jammu Tawi, 180001, India. Electronic address: qphas

Bioorg Med Chem Lett ; 27(11): 2579-2582, 2017 06 01.

Article em En | MEDLINE | ID: mdl-28400238

Assuntos

Actinobacteria/química; Antibacterianos/química; Antineoplásicos/química; Sesquiterpenos de Eudesmano/química; Actinobacteria/metabolismo; Antibacterianos/isolamento & purificação; Antibacterianos/farmacologia; Antineoplásicos/isolamento & purificação; Antineoplásicos/toxicidade; Linhagem Celular Tumoral; Sobrevivência Celular/efeitos dos fármacos; Bactérias Gram-Negativas/efeitos dos fármacos; Bactérias Gram-Positivas/efeitos dos fármacos; Humanos; Espectroscopia de Ressonância Magnética; Testes de Sensibilidade Microbiana; Conformação Molecular; Sesquiterpenos de Eudesmano/isolamento & purificação; Sesquiterpenos de Eudesmano/farmacologia; Espectrometria de Massas por Ionização por Electrospray; Espectroscopia de Infravermelho com Transformada de Fourier

Palavras-chave

Actinomycetes; Antitumor and antimicrobial activity; Bioactive compounds; Lentzea violacea

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Actinobacteria / Sesquiterpenos de Eudesmano / Antibacterianos / Antineoplásicos Limite: Humans Idioma: En Revista: Bioorg Med Chem Lett Assunto da revista: BIOQUIMICA / QUIMICA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Índia

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