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How Well Does CAPTURE Translate?: An Exploratory Analysis of a COPD Case-Finding Method for Spanish-Speaking Patients.
Quezada, Wilson A; Whippo, Beth A; Jellen, Patricia A; Leidy, Nancy K; Mannino, David M; Kim, Katherine J; Han, MeiLan K; Houfek, Julia F; Make, Barry; Malley, Karen G; Meldrum, Catherine A; Rennard, Stephen I; Yawn, Barbara P; Martinez, Fernando J; Thomashow, Byron M.
Afiliação
  • Quezada WA; Columbia University, New York, NY.
  • Whippo BA; NewYork-Presbyterian Hospital/Columbia University Medical Center, New York, NY.
  • Jellen PA; NewYork-Presbyterian Hospital/Columbia University Medical Center, New York, NY.
  • Leidy NK; Evidera, Bethesda, MD.
  • Mannino DM; University of Kentucky, Lexington, KY.
  • Kim KJ; Evidera, Bethesda, MD.
  • Han MK; University of Michigan, Ann Arbor, MI.
  • Houfek JF; University of Nebraska, Omaha, NE.
  • Make B; National Jewish Health, Denver, CO.
  • Malley KG; Evidera, Bethesda, MD.
  • Meldrum CA; University of Michigan, Ann Arbor, MI.
  • Rennard SI; University of Nebraska, Omaha, NE; AstraZeneca, Cambridge, UK.
  • Yawn BP; University of Minnesota, Minneapolis, MN.
  • Martinez FJ; Cornell University, New York, NY. Electronic address: fjm2003@med.cornell.edu.
  • Thomashow BM; Columbia University, New York, NY.
Chest ; 152(4): 761-770, 2017 10.
Article em En | MEDLINE | ID: mdl-28414029
BACKGROUND: This study tested the properties of a Spanish translation of CAPTURE (COPD Assessment in Primary Care To Identify Undiagnosed Respiratory Disease and Exacerbation Risk) with selective use of peak expiratory flow (PEF). METHODS: This study comprised analyses of data from the Spanish-speaking cohort of the cross-sectional, case-control study used to develop CAPTURE. Translation procedures included forward and backward translation, reconciliation, and cognitive interviewing to assure linguistic and cultural equivalence, yielding CAPTURE-S. Spanish-speaking participants were recruited through one center and designated as case subjects (clinically significant COPD: FEV1 ≤ 60% predicted and/or at risk of COPD exacerbation) or control subjects (no or mild COPD). Subjects completed a questionnaire booklet that included 44 candidate items, the COPD Assessment Test (CAT), and the modified Medical Research Council (mMRC) dyspnea question. PEF and spirometry were also performed. RESULTS: The study included 30 participants (17 case subjects and 13 control subjects). Their mean (± SD) age was 62.6 (11.49) years, and 33% were male. CAPTURE-S scores were significantly correlated with PEF (r = -0.78), the FEV1/FVC ratio (r = -0.74), FEV1 (r = -0.69), FEV1 % predicted (r = -0.69), the CAT score (r = 0.70), and the mMRC dyspnea question (r = 0.59) (P < .0001), with significantly higher scores in case subjects than in control subjects (t = 6.16; P < .0001). PEF significantly correlated with FEV1 (r = 0.89), FEV1 % predicted (r = 0.79), and the FEV1/FVC ratio (r = 0.75) (P < .0001), with significantly lower PEF in case subjects than in control subjects (t = 5.08; P < .0001). CAPTURE-S score + PEF differentiated case subjects and control subjects with a sensitivity of 88.2% and a specificity of 92.3%. CONCLUSIONS: CAPTURE-S with selective use of PEF seems to be useful for identifying Spanish-speaking patients in need of diagnostic evaluation for clinically significant COPD who may benefit from initiation of COPD treatment. TRIAL REGISTRY: ClinicalTrials.gov; No.: NCT01880177; URL: www.clinicaltrials.gov.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Espirometria / Traduções / Hispânico ou Latino / Volume Expiratório Forçado / Avaliação de Resultados em Cuidados de Saúde / Doença Pulmonar Obstrutiva Crônica Tipo de estudo: Clinical_trials / Diagnostic_studies / Observational_studies / Prevalence_studies / Prognostic_studies Limite: Aged / Female / Humans / Male / Middle aged País/Região como assunto: America do norte Idioma: En Revista: Chest Ano de publicação: 2017 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Espirometria / Traduções / Hispânico ou Latino / Volume Expiratório Forçado / Avaliação de Resultados em Cuidados de Saúde / Doença Pulmonar Obstrutiva Crônica Tipo de estudo: Clinical_trials / Diagnostic_studies / Observational_studies / Prevalence_studies / Prognostic_studies Limite: Aged / Female / Humans / Male / Middle aged País/Região como assunto: America do norte Idioma: En Revista: Chest Ano de publicação: 2017 Tipo de documento: Article