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Bis-anthracycline WP760 abrogates melanoma cell growth by transcription inhibition, p53 activation and IGF1R downregulation.
Olbryt, Magdalena; Rusin, Aleksandra; Fokt, Izabela; Habryka, Anna; Tudrej, Patrycja; Student, Sebastian; Sochanik, Aleksander; Zielinski, Rafal; Priebe, Waldemar.
Afiliação
  • Olbryt M; Center for Translational Research and Molecular Biology of Cancer, Maria Sklodowska-Curie Memorial Cancer Center and Institute of Oncology, Gliwice Branch, Wybrzeze Armii Krajowej 15, 44-101, Gliwice, Poland. Magdalena.Olbryt@io.gliwice.pl.
  • Rusin A; Center for Translational Research and Molecular Biology of Cancer, Maria Sklodowska-Curie Memorial Cancer Center and Institute of Oncology, Gliwice Branch, Wybrzeze Armii Krajowej 15, 44-101, Gliwice, Poland.
  • Fokt I; Department of Experimental Therapeutics, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Habryka A; Department of Experimental Therapeutics, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Tudrej P; Center for Translational Research and Molecular Biology of Cancer, Maria Sklodowska-Curie Memorial Cancer Center and Institute of Oncology, Gliwice Branch, Wybrzeze Armii Krajowej 15, 44-101, Gliwice, Poland.
  • Student S; Center for Translational Research and Molecular Biology of Cancer, Maria Sklodowska-Curie Memorial Cancer Center and Institute of Oncology, Gliwice Branch, Wybrzeze Armii Krajowej 15, 44-101, Gliwice, Poland.
  • Sochanik A; Faculty of Automatic Control, Electronics and Computer Science, Silesian University of Technology, Gliwice, Poland.
  • Zielinski R; Center for Translational Research and Molecular Biology of Cancer, Maria Sklodowska-Curie Memorial Cancer Center and Institute of Oncology, Gliwice Branch, Wybrzeze Armii Krajowej 15, 44-101, Gliwice, Poland.
  • Priebe W; Department of Experimental Therapeutics, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Invest New Drugs ; 35(5): 545-555, 2017 Oct.
Article em En | MEDLINE | ID: mdl-28417283

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transcrição Gênica / Proteína Supressora de Tumor p53 / Receptores de Somatomedina / Antraciclinas / Proliferação de Células / Melanoma Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Invest New Drugs Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Polônia

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transcrição Gênica / Proteína Supressora de Tumor p53 / Receptores de Somatomedina / Antraciclinas / Proliferação de Células / Melanoma Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Invest New Drugs Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Polônia