Time course of upper limb function and return-to-work post-radiotherapy in young adults with breast cancer: a pilot randomized control trial on effects of targeted exercise program.
J Cancer Surviv
; 11(6): 791-799, 2017 Dec.
Article
em En
| MEDLINE
| ID: mdl-28470507
ABSTRACT
PURPOSE:
Breast cancer (BC) diagnosis in young adults (YA) is rising, and both disease and treatments are aggressive in this population. Evidence supports the use of physical activity in reducing shoulder dysfunction, which is common among BC survivors. A pilot randomized clinical trial was performed to determine the effectiveness of a 12-week post-radiation exercise program in minimizing upper extremity dysfunction in YA with BC.METHODS:
Participants were randomized to either an exercise arm or a control arm receiving standard care. Data was collected over six time points using the Disability of Arm, Shoulder, and Hand (DASH); the Metabolic Equivalent of Task-hours per week (MET-hours/week), and a post hoc questionnaire on return to work.RESULTS:
In total, 59 young women participated in the study (n = 29 exercise; n = 30 control). No statistically significant differences were found in overall DASH results between groups; however, those who underwent total mastectomy had residual upper limb dysfunction (p < 0.05). Both groups returned to pre-diagnosis activity levels by 18 months. Final evaluation showed that 86% of the women returned to work, and 89% resumed prior work activities with a decrease of 8.5 h/week.CONCLUSION:
Although the short-term targeted exercise program had no effect on long-term upper limb function post-radiation, timing and program specificity may require consideration of tissue healing post-radiation and surgery type. The majority of participants returned to work, however not returning to pre-diagnosis work hours. IMPLICATIONS FOR CANCER SURVIVORS Exercise interventions alone may not reverse the long-term sequelae of breast cancer treatment and allow young adult patients to return to work.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Neoplasias da Mama
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Extremidade Superior
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Terapia por Exercício
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Retorno ao Trabalho
Tipo de estudo:
Clinical_trials
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Observational_studies
Limite:
Adolescent
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Adult
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Female
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Humans
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Middle aged
Idioma:
En
Revista:
J Cancer Surviv
Ano de publicação:
2017
Tipo de documento:
Article
País de afiliação:
Canadá