Asymmetric Total Syntheses of (-)-α-Lycorane, (-)-Zephyranthine, and Formal Synthesis of (+)-Clivonine.
Chem Asian J
; 12(12): 1309-1313, 2017 Jun 19.
Article
em En
| MEDLINE
| ID: mdl-28474489
ABSTRACT
An asymmetric route to (-)-α-lycorane and (-)-zephyranthine, and a formal total synthesis of (+)-clivonine were achieved. A pivotal intermediate, which serves as a potent precursor for the divergent syntheses of these natural products, was accessed by a diastereoselective Pd-catalyzed cinnamylation of an N-tert-butanesulfinyl imine.
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1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Fenantridinas
/
Alcaloides de Amaryllidaceae
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Alcaloides
Idioma:
En
Revista:
Chem Asian J
Ano de publicação:
2017
Tipo de documento:
Article
País de afiliação:
China