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Burden of illness and healthcare resource use in United States patients with sporadic inclusion body myositis.
Capkun, Gorana; Callan, Aoife; Tian, Haijun; Wei, Zhongyuan; Zhao, Changgeng; Agashivala, Neetu; Barghout, Victoria.
Afiliação
  • Capkun G; Novartis AG, Basel, Switzerland.
  • Callan A; Novartis Global Service Center Dublin, Ireland.
  • Tian H; Novartis Pharmaceuticals Corporation, East Hanover, New Jersey, USA.
  • Wei Z; KMK Consulting, Inc., Morristown, New Jersey, USA.
  • Zhao C; Novartis Pharmaceuticals Corporation, East Hanover, New Jersey, USA.
  • Agashivala N; Novartis Pharmaceuticals Corporation, East Hanover, New Jersey, USA.
  • Barghout V; VEB HealthCare LLC, Morristown, New Jersey, USA.
Muscle Nerve ; 56(5): 861-867, 2017 Nov.
Article em En | MEDLINE | ID: mdl-28493327
ABSTRACT

INTRODUCTION:

We analyzed the burden of illness of sporadic inclusion body myositis (sIBM) patients and the costs to the healthcare system.

METHODS:

A retrospective cohort analysis of 333 sIBM patients aged ≥ 50 years was performed using United States (U.S.) claims data. sIBM patients were matched in a 15 ratio to randomly selected individuals with ≥1 healthcare encounter within the year of index date.

RESULTS:

sIBM patients presented with higher rates of disease- and muscle-related conditions, such as myalgia, myositis, muscle weakness, dysphagia, pneumonia, and falls. Use of healthcare resources, including physical therapy, office visits, emergency room (ER) visits, and hospitalizations, was greater in sIBM patients. This was also reflected in significantly higher overall healthcare costs in the sIBM population driven mainly by more all-cause office visits, all-cause ER visits and hospitalizations.

CONCLUSIONS:

sIBM imposes a substantial burden on U.S. patients in terms of additional healthcare usage and associated costs. Muscle Nerve 56 861-867, 2017.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Custos de Cuidados de Saúde / Efeitos Psicossociais da Doença / Miosite de Corpos de Inclusão / Recursos em Saúde Tipo de estudo: Observational_studies / Risk_factors_studies Limite: Aged / Aged80 / Female / Humans / Male / Middle aged País/Região como assunto: America do norte Idioma: En Revista: Muscle Nerve Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Suíça

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Custos de Cuidados de Saúde / Efeitos Psicossociais da Doença / Miosite de Corpos de Inclusão / Recursos em Saúde Tipo de estudo: Observational_studies / Risk_factors_studies Limite: Aged / Aged80 / Female / Humans / Male / Middle aged País/Região como assunto: America do norte Idioma: En Revista: Muscle Nerve Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Suíça