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The opioid receptor triple agonist DPI-125 produces analgesia with less respiratory depression and reduced abuse liability.
Yi, Shou-Pu; Kong, Qing-Hong; Li, Yu-Lei; Pan, Chen-Ling; Yu, Jie; Cui, Ben-Qiang; Wang, Ying-Fei; Wang, Guan-Lin; Zhou, Pei-Lan; Wang, Li-Li; Gong, Ze-Hui; Su, Rui-Bin; Shen, Yue-Hai; Yu, Gang; Chang, Kwen-Jen.
Afiliação
  • Yi SP; Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming 650500, China.
  • Kong QH; Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming 650500, China.
  • Li YL; State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Institute of Pharmacology &Toxicology, Beijing 100850, China.
  • Pan CL; Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming 650500, China.
  • Yu J; Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming 650500, China.
  • Cui BQ; Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming 650500, China.
  • Wang YF; Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming 650500, China.
  • Wang GL; Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming 650500, China.
  • Zhou PL; State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Institute of Pharmacology &Toxicology, Beijing 100850, China.
  • Wang LL; Beijing Institute of Pharmacology &Toxicology, Beijing 100850, China.
  • Gong ZH; State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Institute of Pharmacology &Toxicology, Beijing 100850, China.
  • Su RB; State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Institute of Pharmacology &Toxicology, Beijing 100850, China.
  • Shen YH; Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming 650500, China.
  • Yu G; State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, China.
  • Chang KJ; State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Institute of Pharmacology &Toxicology, Beijing 100850, China.
Acta Pharmacol Sin ; 38(7): 977-989, 2017 Jul.
Article em En | MEDLINE | ID: mdl-28502978
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Dor / Piperazinas / Insuficiência Respiratória / Tiofenos / Analgesia / Analgésicos Opioides Tipo de estudo: Prognostic_studies Limite: Animals / Humans / Male Idioma: En Revista: Acta Pharmacol Sin Assunto da revista: FARMACOLOGIA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: China
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Dor / Piperazinas / Insuficiência Respiratória / Tiofenos / Analgesia / Analgésicos Opioides Tipo de estudo: Prognostic_studies Limite: Animals / Humans / Male Idioma: En Revista: Acta Pharmacol Sin Assunto da revista: FARMACOLOGIA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: China