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The PPARγ-SETD8 axis constitutes an epigenetic, p53-independent checkpoint on p21-mediated cellular senescence.
Shih, Chieh-Tien; Chang, Yi-Feng; Chen, Yi-Tung; Ma, Chung-Pei; Chen, Hui-Wen; Yang, Chang-Ching; Lu, Juu-Chin; Tsai, Yau-Sheng; Chen, Hua-Chien; Tan, Bertrand Chin-Ming.
Afiliação
  • Shih CT; Graduate Institute of Biomedical Sciences, College of Medicine, Chang Gung University, Kwei-San, Tao-Yuan, Taiwan.
  • Chang YF; Molecular Medicine Research Center, Chang Gung University, Tao-Yuan, Taiwan.
  • Chen YT; Graduate Institute of Biomedical Sciences, College of Medicine, Chang Gung University, Kwei-San, Tao-Yuan, Taiwan.
  • Ma CP; Graduate Institute of Biomedical Sciences, College of Medicine, Chang Gung University, Kwei-San, Tao-Yuan, Taiwan.
  • Chen HW; Department of Biomedical Sciences, College of Medicine, Chang Gung University, Kwei-San, Tao-Yuan, Taiwan.
  • Yang CC; Graduate Institute of Biomedical Sciences, College of Medicine, Chang Gung University, Kwei-San, Tao-Yuan, Taiwan.
  • Lu JC; Department of Biomedical Sciences, College of Medicine, Chang Gung University, Kwei-San, Tao-Yuan, Taiwan.
  • Tsai YS; Graduate Institute of Biomedical Sciences, College of Medicine, Chang Gung University, Kwei-San, Tao-Yuan, Taiwan.
  • Chen HC; Department of Physiology and Pharmacology, College of Medicine, Chang Gung University, Kwei-San, Tao-Yuan, Taiwan.
  • Tan BC; Division of Endocrinology and Metabolism, Department of Internal Medicine, Chang Gung Memorial Hospital, Linkou, Tao-Yuan, Taiwan.
Aging Cell ; 16(4): 797-813, 2017 08.
Article em En | MEDLINE | ID: mdl-28514051
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Histona-Lisina N-Metiltransferase / Senescência Celular / Epigênese Genética / PPAR gama / Inibidor de Quinase Dependente de Ciclina p21 / Fibroblastos Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Aging Cell Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Taiwan
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Histona-Lisina N-Metiltransferase / Senescência Celular / Epigênese Genética / PPAR gama / Inibidor de Quinase Dependente de Ciclina p21 / Fibroblastos Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Aging Cell Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Taiwan