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SMAD4 Loss Is Associated with Cetuximab Resistance and Induction of MAPK/JNK Activation in Head and Neck Cancer Cells.
Ozawa, Hiroyuki; Ranaweera, Ruchira S; Izumchenko, Evgeny; Makarev, Eugene; Zhavoronkov, Alex; Fertig, Elana J; Howard, Jason D; Markovic, Ana; Bedi, Atul; Ravi, Rajani; Perez, Jimena; Le, Quynh-Thu; Kong, Christina S; Jordan, Richard C; Wang, Hao; Kang, Hyunseok; Quon, Harry; Sidransky, David; Chung, Christine H.
Afiliação
  • Ozawa H; Department of Oncology, School of Medicine, Johns Hopkins University, Baltimore, Maryland.
  • Ranaweera RS; Department of Oncology, School of Medicine, Johns Hopkins University, Baltimore, Maryland.
  • Izumchenko E; Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland.
  • Makarev E; Insilico Medicine, Inc, ETC, Johns Hopkins University, Baltimore, Maryland.
  • Zhavoronkov A; Insilico Medicine, Inc, ETC, Johns Hopkins University, Baltimore, Maryland.
  • Fertig EJ; Department of Oncology, School of Medicine, Johns Hopkins University, Baltimore, Maryland.
  • Howard JD; Department of Health Science Informatics, Johns Hopkins University, Baltimore, Maryland.
  • Markovic A; Department of Oncology, School of Medicine, Johns Hopkins University, Baltimore, Maryland.
  • Bedi A; Department of Oncology, School of Medicine, Johns Hopkins University, Baltimore, Maryland.
  • Ravi R; Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland.
  • Perez J; Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland.
  • Le QT; Department of Oncology, School of Medicine, Johns Hopkins University, Baltimore, Maryland.
  • Kong CS; Department of Pathology, Stanford University School of Medicine Stanford, California.
  • Jordan RC; Department of Pathology, Stanford University School of Medicine Stanford, California.
  • Wang H; Departments of Orofacial Sciences and Pathology, University of California, San Francisco, San Francisco, CA, USA.
  • Kang H; Department of Oncology, School of Medicine, Johns Hopkins University, Baltimore, Maryland.
  • Quon H; Department of Oncology, School of Medicine, Johns Hopkins University, Baltimore, Maryland.
  • Sidransky D; Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Baltimore, Maryland.
  • Chung CH; Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Clin Cancer Res ; 23(17): 5162-5175, 2017 Sep 01.
Article em En | MEDLINE | ID: mdl-28522603
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Resistencia a Medicamentos Antineoplásicos / Proteína Smad4 / Neoplasias de Cabeça e Pescoço / Recidiva Local de Neoplasia Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Aged / Animals / Female / Humans / Middle aged Idioma: En Revista: Clin Cancer Res Assunto da revista: NEOPLASIAS Ano de publicação: 2017 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Resistencia a Medicamentos Antineoplásicos / Proteína Smad4 / Neoplasias de Cabeça e Pescoço / Recidiva Local de Neoplasia Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Aged / Animals / Female / Humans / Middle aged Idioma: En Revista: Clin Cancer Res Assunto da revista: NEOPLASIAS Ano de publicação: 2017 Tipo de documento: Article