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A conformational switch high-throughput screening assay and allosteric inhibition of the flavivirus NS2B-NS3 protease.
Brecher, Matthew; Li, Zhong; Liu, Binbin; Zhang, Jing; Koetzner, Cheri A; Alifarag, Adham; Jones, Susan A; Lin, Qishan; Kramer, Laura D; Li, Hongmin.
Afiliação
  • Brecher M; Wadsworth Center, New York State Department of Health, 120 New Scotland Ave, Albany NY, United States of America.
  • Li Z; Wadsworth Center, New York State Department of Health, 120 New Scotland Ave, Albany NY, United States of America.
  • Liu B; Wadsworth Center, New York State Department of Health, 120 New Scotland Ave, Albany NY, United States of America.
  • Zhang J; Department of food science, College of food science and technology, Guangdong Ocean University, Zhanjiang, Guangdong, People's Republic of China.
  • Koetzner CA; Wadsworth Center, New York State Department of Health, 120 New Scotland Ave, Albany NY, United States of America.
  • Alifarag A; Wadsworth Center, New York State Department of Health, 120 New Scotland Ave, Albany NY, United States of America.
  • Jones SA; Wadsworth Center, New York State Department of Health, 120 New Scotland Ave, Albany NY, United States of America.
  • Lin Q; Wadsworth Center, New York State Department of Health, 120 New Scotland Ave, Albany NY, United States of America.
  • Kramer LD; Center for Functional Genomics, University at Albany, Rensselaer, New York, United States of America.
  • Li H; Wadsworth Center, New York State Department of Health, 120 New Scotland Ave, Albany NY, United States of America.
PLoS Pathog ; 13(5): e1006411, 2017 May.
Article em En | MEDLINE | ID: mdl-28542603
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas não Estruturais Virais / Inibidores Enzimáticos / Ensaios de Triagem em Larga Escala / Flavivirus Tipo de estudo: Diagnostic_studies / Evaluation_studies / Screening_studies Idioma: En Revista: PLoS Pathog Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas não Estruturais Virais / Inibidores Enzimáticos / Ensaios de Triagem em Larga Escala / Flavivirus Tipo de estudo: Diagnostic_studies / Evaluation_studies / Screening_studies Idioma: En Revista: PLoS Pathog Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Estados Unidos