MicroRNA-186-5p overexpression modulates colon cancer growth by repressing the expression of the FAM134B tumour inhibitor.

Islam, Farhadul; Gopalan, Vinod; Vider, Jelena; Wahab, Riajul; Ebrahimi, Faeza; Lu, Cu-Tai; Kasem, Kais; Lam, Alfred K Y

Islam, Farhadul; Gopalan, Vinod; Vider, Jelena; Wahab, Riajul; Ebrahimi, Faeza; Lu, Cu-Tai; Kasem, Kais; Lam, Alfred K Y.

Afiliação

Islam F; Cancer Molecular Pathology, School of Medicine and Menzies Health Institute Queensland, Griffith University, Gold Coast, Queensland, Australia; Department of Biochemistry and Molecular Biology, University of Rajshahi, Rajshahi 6205, Bangladesh.
Gopalan V; Cancer Molecular Pathology, School of Medicine and Menzies Health Institute Queensland, Griffith University, Gold Coast, Queensland, Australia.
Vider J; School of Medical Science and Menzies Health Institute Queensland, Griffith University, Gold Coast, Queensland, Australia.
Wahab R; Cancer Molecular Pathology, School of Medicine and Menzies Health Institute Queensland, Griffith University, Gold Coast, Queensland, Australia.
Ebrahimi F; Cancer Molecular Pathology, School of Medicine and Menzies Health Institute Queensland, Griffith University, Gold Coast, Queensland, Australia.
Lu CT; Department of Surgery, Gold Coast Hospital, Gold Coast, Queensland, Australia.
Kasem K; Cancer Molecular Pathology, School of Medicine and Menzies Health Institute Queensland, Griffith University, Gold Coast, Queensland, Australia.
Lam AKY; Cancer Molecular Pathology, School of Medicine and Menzies Health Institute Queensland, Griffith University, Gold Coast, Queensland, Australia. Electronic address: a.lam@griffith.edu.au.

Exp Cell Res ; 357(2): 260-270, 2017 08 15.

Article em En | MEDLINE | ID: mdl-28549913

Assuntos

Proliferação de Células/genética; Neoplasias do Colo/genética; Regulação Neoplásica da Expressão Gênica/genética; MicroRNAs/genética; Proteínas de Neoplasias/metabolismo; Adulto; Idoso; Idoso de 80 Anos ou mais; Linhagem Celular Tumoral; Movimento Celular/genética; Neoplasias do Colo/patologia; Feminino; Genes Supressores de Tumor; Humanos; Peptídeos e Proteínas de Sinalização Intracelular; Masculino; Proteínas de Membrana; Pessoa de Meia-Idade; Proteínas de Neoplasias/genética

Palavras-chave

Colorectal cancer; FAM134B; Oncogenic micro-RNA; Targeted therapy; miR-186-5p

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Regulação Neoplásica da Expressão Gênica / Neoplasias do Colo / MicroRNAs / Proliferação de Células / Proteínas de Neoplasias Limite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Exp Cell Res Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Bangladesh

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