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Synthesis and Preliminary Studies of a Novel Negative Allosteric Modulator, 7-((2,5-Dioxopyrrolidin-1-yl)methyl)-4-(2-fluoro-4-[11C]methoxyphenyl) quinoline-2-carboxamide, for Imaging of Metabotropic Glutamate Receptor 2.
Zhang, Xiaofei; Kumata, Katsushi; Yamasaki, Tomoteru; Cheng, Ran; Hatori, Akiko; Ma, Longle; Zhang, Yiding; Xie, Lin; Wang, Lu; Kang, Hye Jin; Sheffler, Douglas J; Cosford, Nicholas D P; Zhang, Ming-Rong; Liang, Steven H.
Afiliação
  • Zhang X; Nuclear Medicine and Molecular Imaging, Massachusetts General Hospital , Boston, Massachusetts 02114, United States.
  • Kumata K; Department of Radiology, Harvard Medical School , Boston, Massachusetts 02114, United States.
  • Yamasaki T; State Key Laboratory and Institute of Elemento-Organic Chemistry, Collaborative Innovation Center of Chemical Science and Engineering, Nankai Unviersity , Tianjin 300071, China.
  • Cheng R; Department of Radiopharmaceutics Development, National Institute of Radiological Sciences, National Institutes for Quantum and Radiological Science and Technology , Chiba 263-8555, Japan.
  • Hatori A; Department of Radiopharmaceutics Development, National Institute of Radiological Sciences, National Institutes for Quantum and Radiological Science and Technology , Chiba 263-8555, Japan.
  • Ma L; Nuclear Medicine and Molecular Imaging, Massachusetts General Hospital , Boston, Massachusetts 02114, United States.
  • Zhang Y; Department of Radiology, Harvard Medical School , Boston, Massachusetts 02114, United States.
  • Xie L; Department of Radiopharmaceutics Development, National Institute of Radiological Sciences, National Institutes for Quantum and Radiological Science and Technology , Chiba 263-8555, Japan.
  • Wang L; Nuclear Medicine and Molecular Imaging, Massachusetts General Hospital , Boston, Massachusetts 02114, United States.
  • Kang HJ; Department of Radiology, Harvard Medical School , Boston, Massachusetts 02114, United States.
  • Sheffler DJ; Department of Radiopharmaceutics Development, National Institute of Radiological Sciences, National Institutes for Quantum and Radiological Science and Technology , Chiba 263-8555, Japan.
  • Cosford NDP; Department of Radiopharmaceutics Development, National Institute of Radiological Sciences, National Institutes for Quantum and Radiological Science and Technology , Chiba 263-8555, Japan.
  • Zhang MR; Nuclear Medicine and Molecular Imaging, Massachusetts General Hospital , Boston, Massachusetts 02114, United States.
  • Liang SH; Department of Radiology, Harvard Medical School , Boston, Massachusetts 02114, United States.
ACS Chem Neurosci ; 8(9): 1937-1948, 2017 09 20.
Article em En | MEDLINE | ID: mdl-28565908
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pirrolidinas / Quinolinas / Encéfalo / Receptores de Glutamato Metabotrópico / Compostos Radiofarmacêuticos / Tomografia por Emissão de Pósitrons Limite: Animals / Humans / Male Idioma: En Revista: ACS Chem Neurosci Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pirrolidinas / Quinolinas / Encéfalo / Receptores de Glutamato Metabotrópico / Compostos Radiofarmacêuticos / Tomografia por Emissão de Pósitrons Limite: Animals / Humans / Male Idioma: En Revista: ACS Chem Neurosci Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Estados Unidos