The integration of multiple signaling pathways provides for bidirectional control of CRHR1 gene transcription in rat pituitary cell during hypoxia.

Shi, Yan Jun; Ma, Zhi Qiang; Tang, Jia Wei; Zhao, Yang; Wang, Xi; Liu, Qing; Wang, Ping Ping; John, Coote; Chen, Xue Qun; Du, Ji Zeng

Shi, Yan Jun; Ma, Zhi Qiang; Tang, Jia Wei; Zhao, Yang; Wang, Xi; Liu, Qing; Wang, Ping Ping; John, Coote; Chen, Xue Qun; Du, Ji Zeng.

Afiliação

Shi YJ; Division of Neurobiology and Physiology, Department of Basic Medical Sciences, School of Medicine, Zhejiang University, Hangzhou, 310058, China.
Ma ZQ; Division of Neurobiology and Physiology, Department of Basic Medical Sciences, School of Medicine, Zhejiang University, Hangzhou, 310058, China.
Tang JW; Division of Neurobiology and Physiology, Department of Basic Medical Sciences, School of Medicine, Zhejiang University, Hangzhou, 310058, China.
Zhao Y; Division of Neurobiology and Physiology, Department of Basic Medical Sciences, School of Medicine, Zhejiang University, Hangzhou, 310058, China.
Wang X; Division of Neurobiology and Physiology, Department of Basic Medical Sciences, School of Medicine, Zhejiang University, Hangzhou, 310058, China.
Liu Q; WHO Collaborating Center for Research in Human Reproduction, Division of Science and Technology & Foreign Affairs, National Research Institute for Family Planning, Beijing, 100081, China.
Wang PP; Division of Neurobiology and Physiology, Department of Basic Medical Sciences, School of Medicine, Zhejiang University, Hangzhou, 310058, China.
John C; School of Clinical and Experimental Medicine, University of Birmingham, Birmingham, B15 2TT, UK.
Chen XQ; Division of Neurobiology and Physiology, Department of Basic Medical Sciences, School of Medicine, Zhejiang University, Hangzhou, 310058, China; Key Laboratory of Medical Neurobiology, The Ministry of Health, China; Zhejiang Province Key Laboratory for Neurobiology, Hangzhou, 310058, China. Electron
Du JZ; Division of Neurobiology and Physiology, Department of Basic Medical Sciences, School of Medicine, Zhejiang University, Hangzhou, 310058, China; Key Laboratory of Medical Neurobiology, The Ministry of Health, China; Zhejiang Province Key Laboratory for Neurobiology, Hangzhou, 310058, China. Electron

Mol Cell Endocrinol ; 454: 12-22, 2017 10 15.

Article em En | MEDLINE | ID: mdl-28572045

Assuntos

Hipófise/patologia; Receptores de Hormônio Liberador da Corticotropina/genética; Transdução de Sinais; Transcrição Gênica; Animais; Encéfalo/embriologia; Hipóxia Celular/genética; Linhagem Celular; Metilação de DNA/genética; Feminino; Subunidade alfa do Fator 1 Induzível por Hipóxia/metabolismo; Masculino; Modelos Biológicos; NF-kappa B/metabolismo; Gravidez; Regiões Promotoras Genéticas/genética; Ligação Proteica; RNA Mensageiro/genética; RNA Mensageiro/metabolismo; Ratos Sprague-Dawley; Receptores de Hormônio Liberador da Corticotropina/metabolismo; Fator de Transcrição AP-1/metabolismo

Palavras-chave

AP-1; CRH; Corticotrophin-releasing hormone receptor 1; Hypoxia; NF-κB; Transcription

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Hipófise / Transcrição Gênica / Transdução de Sinais / Receptores de Hormônio Liberador da Corticotropina Tipo de estudo: Prognostic_studies Limite: Animals / Pregnancy Idioma: En Revista: Mol Cell Endocrinol Ano de publicação: 2017 Tipo de documento: Article País de afiliação: China

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