[Collagen types ratio in prediction of postoperative ventral hernias]. / Sootnoshenie tipov kollagena v prognozirovanii posleoperatsionnykh ventral'nykh gryzh.
Khirurgiia (Mosk)
; (6): 33-36, 2017.
Article
em Ru
| MEDLINE
| ID: mdl-28638011
ABSTRACT
AIM:
To analyze collagen types ratio in skin and aponeurosis in order to predict postoperative ventral hernias. MATERIAL ANDMETHODS:
The trial included 141 patients for the period 2012-2015. Group I (n=65) of patients without ventral hernias was divided into subgroup AI (primary operation, n=41) and BI (re-operation, n=24). Group II consisted of 76 patients with ventral hernias. We performed histological examination of skin and aponeurosis to define the collagen structure of connective tissue.RESULTS:
There were significant differences between collagen type I/III ratio in skin (2.81±0.52 in group I vs. 1.13±0.48 in group II) and aponeurosis (2.69±0.41 vs. 1.09±0.21, respectively, p≤0.05). We revealed strong direct correlation (r=+0.92) between aponeurosis and skin specimens in one group. Collagen type I level was 73.81±2.74% in subgroup AI and 72.03±2.47% in subgroup BI. Collagen type I was predominant (p≤0.05).CONCLUSION:
In patients with ventral hernias collagen type I/III ratio in skin is 2.54 times lower than in patients without hernias. Significant correlation of collagen types in skin and aponeurosis (r= +0.92) allows to predict the risk of postoperative ventral hernias on basis of skin fragment.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Reoperação
/
Pele
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Procedimentos Cirúrgicos Operatórios
/
Colágeno Tipo I
/
Colágeno Tipo III
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Hérnia Incisional
/
Aponeurose
/
Hérnia Ventral
Tipo de estudo:
Clinical_trials
/
Diagnostic_studies
/
Etiology_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Female
/
Humans
/
Male
/
Middle aged
Idioma:
Ru
Revista:
Khirurgiia (Mosk)
Ano de publicação:
2017
Tipo de documento:
Article
País de afiliação:
Federação Russa