On the aquatic toxicity of substituted phenols to Chlorella vulgaris: QSTR with an extended novel data set and interspecies models.
J Hazard Mater
; 339: 122-130, 2017 Oct 05.
Article
em En
| MEDLINE
| ID: mdl-28641232
ABSTRACT
This study provides for the first time the 96-h toxicity of 16 nitro- and methyl- substituted phenols to Chlorella vulgaris. Enabling the circulation of new ecotoxicity data has expanded the previously reported toxicity data set of 30 phenols to C. vulgaris by our laboratory. In this respect, high quality, single source algal toxicity data, generated in the same laboratory according to a REACH (Registration, Evaluation, Authorization and Restriction of CHemicals) compatible endpoint, provided a sound basis to explore quantitative structure-toxicity relationship (QSTR), which can be used for regulatory purposes. Of the developed linear models on a new data set, the selected one was applied to a data set lack of toxicity values, and prediction ability of the model was discussed. Interspecies relations were sought related to Pseudokirchneriella subcapitata and Tetrahymena pyriformis. The developed models displayed decent predictivity, which can be used to predict the toxicity of untested phenols on C. vulgaris.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Fenóis
/
Poluentes Químicos da Água
/
Modelos Lineares
/
Chlorella vulgaris
Tipo de estudo:
Prognostic_studies
Idioma:
En
Revista:
J Hazard Mater
Assunto da revista:
SAUDE AMBIENTAL
Ano de publicação:
2017
Tipo de documento:
Article
País de afiliação:
Turquia