Tropomyosin receptor kinase C (TrkC) expression in medulloblastoma: relation to the molecular subgroups and impact on treatment response.

Friedrich, Carsten; Shalaby, Tarek; Oehler, Christoph; Pruschy, Martin; Seifert, Burkhardt; Picard, Daniel; Remke, Marc; Warmuth-Metz, Monika; Kortmann, Rolf-Dieter; Rutkowski, Stefan; Grotzer, Michael A; von Bueren, André O

Friedrich, Carsten; Shalaby, Tarek; Oehler, Christoph; Pruschy, Martin; Seifert, Burkhardt; Picard, Daniel; Remke, Marc; Warmuth-Metz, Monika; Kortmann, Rolf-Dieter; Rutkowski, Stefan; Grotzer, Michael A; von Bueren, André O.

Afiliação

Friedrich C; Division of Pediatric Oncology and Hematology, University Children's Hospital Rostock, Ernst-Heydemann-Str. 8, 18057, Rostock, Germany. contact.cfriedri@gmail.com.
Shalaby T; Division of Pediatric Oncology, Hematology and Hemostaseology, Department of Women's and Children's Health, University Hospital Leipzig, Leipzig, Germany. contact.cfriedri@gmail.com.
Oehler C; Department of Oncology, University Children's Hospital, Zürich, Switzerland.
Pruschy M; Department of Radiation Oncology, University Hospital Zürich, Zurich, Switzerland.
Seifert B; Department of Radiation Oncology, Hospital Graubünden, Chur, Switzerland.
Picard D; Laboratory for Molecular Radiobiology, Radiation Oncology, University Hospital Zürich, Zürich, Switzerland.
Remke M; Department of Biostatistics, Epidemiology, Biostatistics and Prevention Institute, University of Zurich, Zurich, Switzerland.
Warmuth-Metz M; Department of Pediatric Neuro-Oncogenomics, German Cancer Consortium (DKTK) and German Cancer Research Center (DKFZ), Düsseldorf, Germany.
Kortmann RD; Department of Pediatric Oncology, Hematology and Clinical Immunology, Heinrich-Heine University Düsseldorf, Düsseldorf, Germany.
Rutkowski S; Department of Neuropathology, Medical Faculty, Heinrich-Heine University Düsseldorf, Düsseldorf, Germany.
Grotzer MA; Department of Pediatric Neuro-Oncogenomics, German Cancer Consortium (DKTK) and German Cancer Research Center (DKFZ), Düsseldorf, Germany.
von Bueren AO; Department of Pediatric Oncology, Hematology and Clinical Immunology, Heinrich-Heine University Düsseldorf, Düsseldorf, Germany.

Childs Nerv Syst ; 33(9): 1463-1471, 2017 Sep.

Article em En | MEDLINE | ID: mdl-28695340

Assuntos

Biomarcadores Tumorais/análise; Neoplasias Cerebelares/patologia; Meduloblastoma/patologia; Receptor trkC/biossíntese; Adolescente; Neoplasias Cerebelares/genética; Criança; Pré-Escolar; Feminino; Humanos; Lactente; Masculino; Meduloblastoma/genética; Ensaios Clínicos Controlados Aleatórios como Assunto; Receptor trkC/análise; Adulto Jovem

Palavras-chave

Molecular marker; Molecular subgroups; Response to therapy

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Biomarcadores Tumorais / Neoplasias Cerebelares / Receptor trkC / Meduloblastoma Tipo de estudo: Clinical_trials Limite: Adolescent / Adult / Child / Child, preschool / Female / Humans / Infant / Male Idioma: En Revista: Childs Nerv Syst Assunto da revista: NEUROLOGIA / PEDIATRIA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Alemanha

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