Twenty-Year Progression Rate to Clinical Onset According to Autoantibody Profile, Age, and <i>HLA-DQ</i> Genotype in a Registry-Based Group of Children and Adults With a First-Degree Relative With Type 1 Diabetes.

Gorus, Frans K; Balti, Eric V; Messaaoui, Anissa; Demeester, Simke; Van Dalem, Annelien; Costa, Olivier; Dorchy, Harry; Mathieu, Chantal; Van Gaal, Luc; Keymeulen, Bart; Pipeleers, Daniël G; Weets, Ilse

Twenty-Year Progression Rate to Clinical Onset According to Autoantibody Profile, Age, and HLA-DQ Genotype in a Registry-Based Group of Children and Adults With a First-Degree Relative With Type 1 Diabetes.

Gorus, Frans K; Balti, Eric V; Messaaoui, Anissa; Demeester, Simke; Van Dalem, Annelien; Costa, Olivier; Dorchy, Harry; Mathieu, Chantal; Van Gaal, Luc; Keymeulen, Bart; Pipeleers, Daniël G; Weets, Ilse.

Afiliação

Gorus FK; Diabetes Research Center, Vrije Universiteit Brussel, Brussels, Belgium.
Balti EV; Department of Clinical Chemistry, Universitair Ziekenhuis Brussel, Brussels, Belgium.
Messaaoui A; Diabetes Research Center, Vrije Universiteit Brussel, Brussels, Belgium.
Demeester S; Department of Clinical Chemistry, Universitair Ziekenhuis Brussel, Brussels, Belgium.
Van Dalem A; Department of Diabetology, Hôpital Universitaire des Enfants Reine Fabiola, Brussels, Belgium.
Costa O; Diabetes Research Center, Vrije Universiteit Brussel, Brussels, Belgium.
Dorchy H; Department of Clinical Chemistry, Universitair Ziekenhuis Brussel, Brussels, Belgium.
Mathieu C; Diabetes Research Center, Vrije Universiteit Brussel, Brussels, Belgium.
Van Gaal L; Department of Clinical Chemistry, Universitair Ziekenhuis Brussel, Brussels, Belgium.
Keymeulen B; Diabetes Research Center, Vrije Universiteit Brussel, Brussels, Belgium.
Pipeleers DG; Department of Clinical Chemistry, Universitair Ziekenhuis Brussel, Brussels, Belgium.
Weets I; Department of Diabetology, Hôpital Universitaire des Enfants Reine Fabiola, Brussels, Belgium.

Diabetes Care ; 40(8): 1065-1072, 2017 08.

Article em En | MEDLINE | ID: mdl-28701370

Assuntos

Autoanticorpos/sangue; Diabetes Mellitus Tipo 1/sangue; Progressão da Doença; Antígenos HLA-DQ/genética; Sistema de Registros; Adolescente; Adulto; Bélgica; Criança; Pré-Escolar; Diabetes Mellitus Tipo 1/genética; Feminino; Seguimentos; Humanos; Lactente; Insulina/sangue; Masculino; Modelos de Riscos Proporcionais; Fatores de Risco; Inquéritos e Questionários; Adulto Jovem; Transportador 8 de Zinco/sangue

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Autoanticorpos / Antígenos HLA-DQ / Sistema de Registros / Progressão da Doença / Diabetes Mellitus Tipo 1 Tipo de estudo: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adolescent / Adult / Child / Child, preschool / Female / Humans / Infant / Male País/Região como assunto: Europa Idioma: En Revista: Diabetes Care Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Bélgica

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