Preclinical Models of Ovarian Cancer: Pathogenesis, Problems, and Implications for Prevention.
Clin Obstet Gynecol
; 60(4): 789-800, 2017 12.
Article
em En
| MEDLINE
| ID: mdl-28719396
ABSTRACT
Preclinical models are relatively underutilized and underfunded resources for modeling the pathogenesis and prevention of ovarian cancers. Several reviews have detailed the numerous published models of ovarian cancer. In this review, we will provide an overview of experimental model systems, their strengths and limitations, and use selected models to illustrate how they can be used to address specific issues about ovarian cancer pathogenesis. We will then highlight some of the preclinical prevention studies performed to date and discuss experiments needed to address important unanswered questions about ovarian cancer prevention strategies.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Neoplasias Ovarianas
/
Carcinoma
/
Quimioprevenção
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Procedimentos Cirúrgicos Profiláticos
Tipo de estudo:
Etiology_studies
Limite:
Animals
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Female
/
Humans
Idioma:
En
Revista:
Clin Obstet Gynecol
Ano de publicação:
2017
Tipo de documento:
Article