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Validating Rheumatoid Arthritis Remission Using the Patients' Perspective: Results from a Special Interest Group at OMERACT 2016.
Rasch, Linda A; Boers, Maarten; Hill, Catherine L; Voshaar, Marieke; Hoogland, Wijnanda; de Wit, Maarten; Flurey, Caroline; Davis, Bev; Hetland, Merete Lund; Brahe, Cecilie Heegaard; Gossec, Laure; Wells, George A; Tugwell, Peter; Kuriya, Bindee; Goel, Niti; Singh, Jasvinder A; Duarte, Cátia; Da Silva, José; van Schaardenburg, Dirkjan; Proudman, Susanna; van Tuyl, Lilian H D.
Afiliação
  • Rasch LA; From the Amsterdam Rheumatology and Immunology Center | VU University Medical Center; Epidemiology and Biostatistics, VU University Medical Center, Amsterdam, the Netherlands; Royal Adelaide Hospital and Discipline of Medicine, University of Adelaide, Adelaide, Australia; University of the West of E
  • Boers M; L.A. Rasch, MSc, Amsterdam Rheumatology and Immunology Center | VU University Medical Center; M. Boers, MD, MSc, PhD, Professor, Epidemiology and Biostatistics, VU University Medical Center, and Amsterdam Rheumatology and Immunology Center | Reade; C.L. Hill, MD, Professor, University of Adelaide; M
  • Hill CL; From the Amsterdam Rheumatology and Immunology Center | VU University Medical Center; Epidemiology and Biostatistics, VU University Medical Center, Amsterdam, the Netherlands; Royal Adelaide Hospital and Discipline of Medicine, University of Adelaide, Adelaide, Australia; University of the West of E
  • Voshaar M; L.A. Rasch, MSc, Amsterdam Rheumatology and Immunology Center | VU University Medical Center; M. Boers, MD, MSc, PhD, Professor, Epidemiology and Biostatistics, VU University Medical Center, and Amsterdam Rheumatology and Immunology Center | Reade; C.L. Hill, MD, Professor, University of Adelaide; M
  • Hoogland W; From the Amsterdam Rheumatology and Immunology Center | VU University Medical Center; Epidemiology and Biostatistics, VU University Medical Center, Amsterdam, the Netherlands; Royal Adelaide Hospital and Discipline of Medicine, University of Adelaide, Adelaide, Australia; University of the West of E
  • de Wit M; L.A. Rasch, MSc, Amsterdam Rheumatology and Immunology Center | VU University Medical Center; M. Boers, MD, MSc, PhD, Professor, Epidemiology and Biostatistics, VU University Medical Center, and Amsterdam Rheumatology and Immunology Center | Reade; C.L. Hill, MD, Professor, University of Adelaide; M
  • Flurey C; From the Amsterdam Rheumatology and Immunology Center | VU University Medical Center; Epidemiology and Biostatistics, VU University Medical Center, Amsterdam, the Netherlands; Royal Adelaide Hospital and Discipline of Medicine, University of Adelaide, Adelaide, Australia; University of the West of E
  • Davis B; L.A. Rasch, MSc, Amsterdam Rheumatology and Immunology Center | VU University Medical Center; M. Boers, MD, MSc, PhD, Professor, Epidemiology and Biostatistics, VU University Medical Center, and Amsterdam Rheumatology and Immunology Center | Reade; C.L. Hill, MD, Professor, University of Adelaide; M
  • Hetland ML; From the Amsterdam Rheumatology and Immunology Center | VU University Medical Center; Epidemiology and Biostatistics, VU University Medical Center, Amsterdam, the Netherlands; Royal Adelaide Hospital and Discipline of Medicine, University of Adelaide, Adelaide, Australia; University of the West of E
  • Brahe CH; L.A. Rasch, MSc, Amsterdam Rheumatology and Immunology Center | VU University Medical Center; M. Boers, MD, MSc, PhD, Professor, Epidemiology and Biostatistics, VU University Medical Center, and Amsterdam Rheumatology and Immunology Center | Reade; C.L. Hill, MD, Professor, University of Adelaide; M
  • Gossec L; From the Amsterdam Rheumatology and Immunology Center | VU University Medical Center; Epidemiology and Biostatistics, VU University Medical Center, Amsterdam, the Netherlands; Royal Adelaide Hospital and Discipline of Medicine, University of Adelaide, Adelaide, Australia; University of the West of E
  • Wells GA; L.A. Rasch, MSc, Amsterdam Rheumatology and Immunology Center | VU University Medical Center; M. Boers, MD, MSc, PhD, Professor, Epidemiology and Biostatistics, VU University Medical Center, and Amsterdam Rheumatology and Immunology Center | Reade; C.L. Hill, MD, Professor, University of Adelaide; M
  • Tugwell P; From the Amsterdam Rheumatology and Immunology Center | VU University Medical Center; Epidemiology and Biostatistics, VU University Medical Center, Amsterdam, the Netherlands; Royal Adelaide Hospital and Discipline of Medicine, University of Adelaide, Adelaide, Australia; University of the West of E
  • Kuriya B; L.A. Rasch, MSc, Amsterdam Rheumatology and Immunology Center | VU University Medical Center; M. Boers, MD, MSc, PhD, Professor, Epidemiology and Biostatistics, VU University Medical Center, and Amsterdam Rheumatology and Immunology Center | Reade; C.L. Hill, MD, Professor, University of Adelaide; M
  • Goel N; From the Amsterdam Rheumatology and Immunology Center | VU University Medical Center; Epidemiology and Biostatistics, VU University Medical Center, Amsterdam, the Netherlands; Royal Adelaide Hospital and Discipline of Medicine, University of Adelaide, Adelaide, Australia; University of the West of E
  • Singh JA; L.A. Rasch, MSc, Amsterdam Rheumatology and Immunology Center | VU University Medical Center; M. Boers, MD, MSc, PhD, Professor, Epidemiology and Biostatistics, VU University Medical Center, and Amsterdam Rheumatology and Immunology Center | Reade; C.L. Hill, MD, Professor, University of Adelaide; M
  • Duarte C; From the Amsterdam Rheumatology and Immunology Center | VU University Medical Center; Epidemiology and Biostatistics, VU University Medical Center, Amsterdam, the Netherlands; Royal Adelaide Hospital and Discipline of Medicine, University of Adelaide, Adelaide, Australia; University of the West of E
  • Da Silva J; L.A. Rasch, MSc, Amsterdam Rheumatology and Immunology Center | VU University Medical Center; M. Boers, MD, MSc, PhD, Professor, Epidemiology and Biostatistics, VU University Medical Center, and Amsterdam Rheumatology and Immunology Center | Reade; C.L. Hill, MD, Professor, University of Adelaide; M
  • van Schaardenburg D; From the Amsterdam Rheumatology and Immunology Center | VU University Medical Center; Epidemiology and Biostatistics, VU University Medical Center, Amsterdam, the Netherlands; Royal Adelaide Hospital and Discipline of Medicine, University of Adelaide, Adelaide, Australia; University of the West of E
  • Proudman S; L.A. Rasch, MSc, Amsterdam Rheumatology and Immunology Center | VU University Medical Center; M. Boers, MD, MSc, PhD, Professor, Epidemiology and Biostatistics, VU University Medical Center, and Amsterdam Rheumatology and Immunology Center | Reade; C.L. Hill, MD, Professor, University of Adelaide; M
  • van Tuyl LHD; From the Amsterdam Rheumatology and Immunology Center | VU University Medical Center; Epidemiology and Biostatistics, VU University Medical Center, Amsterdam, the Netherlands; Royal Adelaide Hospital and Discipline of Medicine, University of Adelaide, Adelaide, Australia; University of the West of E
J Rheumatol ; 44(12): 1889-1893, 2017 Dec.
Article em En | MEDLINE | ID: mdl-28765250
ABSTRACT

OBJECTIVE:

The Outcome Measures in Rheumatology (OMERACT) working group on the patients' perspective on remission in rheumatoid arthritis (RA) has been working on this topic since 2010. At OMERACT 2016, progress and preliminary data on validity of measurement instruments for pain, fatigue, and independence in remission in RA were presented, and future directions were explored.

METHODS:

A special interest group was organized, in which the current data on the patients' perspective on remission were presented. The ongoing study that aimed to validate measurement instruments for pain, fatigue, and independence in a state of low disease activity or remission was presented, and preliminary data on construct validity and discriminative capacity were evaluated cross-sectionally.

RESULTS:

At OMERACT 2016, the progress of the working group and preliminary data from 142 of the anticipated 300 patients were presented. Selected instruments significantly correlated with the Disease Activity Score in 28 joints (construct validity) and all instruments except 1 discriminated between patients in and patients not in remission. The subsequent discussion mainly focused around 3 points (1) the formulation of patient perceived remission, (2) the duration of remission, and (3) the measurement of the domain independence. An informal vote indicated a slight preference for working toward modifying the current remission criteria by adding patient-reported outcomes (PRO), or by substituting the patient's global assessment with 1 or more PRO.

CONCLUSION:

More evidence on measuring patients' perspective on remission in RA is needed before an informed decision can be made regarding development or modification of remission definitions.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Participação do Paciente / Artrite Reumatoide / Indução de Remissão / Avaliação de Resultados em Cuidados de Saúde Tipo de estudo: Prognostic_studies / Qualitative_research Limite: Humans Idioma: En Revista: J Rheumatol Ano de publicação: 2017 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Participação do Paciente / Artrite Reumatoide / Indução de Remissão / Avaliação de Resultados em Cuidados de Saúde Tipo de estudo: Prognostic_studies / Qualitative_research Limite: Humans Idioma: En Revista: J Rheumatol Ano de publicação: 2017 Tipo de documento: Article