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Variability in Mass Spectrometry-based Quantification of Clinically Relevant Drug Transporters and Drug Metabolizing Enzymes.
Wegler, Christine; Gaugaz, Fabienne Z; Andersson, Tommy B; Wisniewski, Jacek R; Busch, Diana; Gröer, Christian; Oswald, Stefan; Norén, Agneta; Weiss, Frederik; Hammer, Helen S; Joos, Thomas O; Poetz, Oliver; Achour, Brahim; Rostami-Hodjegan, Amin; van de Steeg, Evita; Wortelboer, Heleen M; Artursson, Per.
Afiliação
  • Wegler C; Department of Pharmacy, Uppsala University , Uppsala 75123, Sweden.
  • Gaugaz FZ; Cardiovascular and Metabolic Diseases, Innovative Medicines and Early Development Biotech Unit, AstraZeneca R&D , Mölndal 431 50, Sweden.
  • Andersson TB; Department of Pharmacy, Uppsala University , Uppsala 75123, Sweden.
  • Wisniewski JR; Cardiovascular and Metabolic Diseases, Innovative Medicines and Early Development Biotech Unit, AstraZeneca R&D , Mölndal 431 50, Sweden.
  • Busch D; Biochemical Proteomics Group, Department of Proteomics and Signal Transduction, Max Planck Institute of Biochemistry , Martinsried 82152, Germany.
  • Gröer C; Center of Drug Absorption and Transport, Department of Clinical Pharmacology, University Medicine of Greifswald , Greifswald 17489, Germany.
  • Oswald S; Center of Drug Absorption and Transport, Department of Clinical Pharmacology, University Medicine of Greifswald , Greifswald 17489, Germany.
  • Norén A; Center of Drug Absorption and Transport, Department of Clinical Pharmacology, University Medicine of Greifswald , Greifswald 17489, Germany.
  • Weiss F; Department of Surgical Sciences, Uppsala University , Uppsala 75185, Sweden.
  • Hammer HS; NMI Natural and Medical Sciences Institute, University of Tübingen , Reutlingen 72770, Germany.
  • Joos TO; NMI Natural and Medical Sciences Institute, University of Tübingen , Reutlingen 72770, Germany.
  • Poetz O; NMI Natural and Medical Sciences Institute, University of Tübingen , Reutlingen 72770, Germany.
  • Achour B; NMI Natural and Medical Sciences Institute, University of Tübingen , Reutlingen 72770, Germany.
  • Rostami-Hodjegan A; Centre for Applied Pharmacokinetic Research, University of Manchester , Manchester M13 9PL, United Kingdom.
  • van de Steeg E; Centre for Applied Pharmacokinetic Research, University of Manchester , Manchester M13 9PL, United Kingdom.
  • Wortelboer HM; TNO (Netherlands Organization for Applied Scientific Research) , 3700 AJ Zeist, Netherlands.
  • Artursson P; TNO (Netherlands Organization for Applied Scientific Research) , 3700 AJ Zeist, Netherlands.
Mol Pharm ; 14(9): 3142-3151, 2017 09 05.
Article em En | MEDLINE | ID: mdl-28767254
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Espectrometria de Massas / Proteômica / Proteínas de Membrana Limite: Humans Idioma: En Revista: Mol Pharm Assunto da revista: BIOLOGIA MOLECULAR / FARMACIA / FARMACOLOGIA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Suécia
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Espectrometria de Massas / Proteômica / Proteínas de Membrana Limite: Humans Idioma: En Revista: Mol Pharm Assunto da revista: BIOLOGIA MOLECULAR / FARMACIA / FARMACOLOGIA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Suécia