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[Q-marker of Chinese medicine and metabolic regularity of co-network compatibility and rainbow potential].
Yang, Yan-Tao; Li, Sen; Liu, Jin-Ling; Zhou, Jin; Zhou, Yi-Qun; Chen, Nai-Hong; He, Fu-Yuan.
Afiliação
  • Yang YT; College of Pharmacy, Hunan University of Chinese Medicine, Changsha 410208, China.
  • Li S; State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China.
  • Liu JL; Druggability and preparation of Chinese Medicine Key Laboratory of Hunan province, Changsha 410208, China.
  • Zhou J; Supramolecular Mechanism and Mathematic-Physics Chracterization for Chinese Materia Medica, Hunan University of Chinese Medicine, Changsha 410208, China.
  • Zhou YQ; College of Pharmacy, Hunan University of Chinese Medicine, Changsha 410208, China.
  • Chen NH; Supramolecular Mechanism and Mathematic-Physics Chracterization for Chinese Materia Medica, Hunan University of Chinese Medicine, Changsha 410208, China.
  • He FY; College of Pharmacy, Hunan University of Chinese Medicine, Changsha 410208, China.
Zhongguo Zhong Yao Za Zhi ; 42(12): 2420-2424, 2017 Jun.
Article em Zh | MEDLINE | ID: mdl-28822202
The effect of Chinese medicine (CM) compound prescription is the combined action results of single herbs based on the basic theory of Chinese medicine, and its function embodies the characteristics of multi components, multi targets and comprehensive effects. It is difficult to study the therapeutic material, establish quality standards or determine Q-marker, so we can't strictly monitor the quality of the whole process of CM. The identification of Q-marker has a profound influence on the whole process of the pharmaceutical engineering of CM. The scattered effect of CM multi-components is regarded as the integral action of the parent nucleus group by the metabolic rule of co-network compatibility and rainbow potential (CCRP). The rule can be used to communicate the individual components and macro components, to reveal the metabolism of CM in organism body and basic law of information exchange, thus revealing the action law of CM on human body. Through the systematic analysis of the Q-marker's guidance to the development of CM and its relationship with the metabolic rule of CCRP, we try to provide some ideas for the identification of Q-marker.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Medicamentos de Ervas Chinesas / Biomarcadores Tipo de estudo: Diagnostic_studies / Guideline / Prognostic_studies Limite: Humans Idioma: Zh Revista: Zhongguo Zhong Yao Za Zhi Assunto da revista: FARMACOLOGIA / TERAPIAS COMPLEMENTARES Ano de publicação: 2017 Tipo de documento: Article País de afiliação: China

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Medicamentos de Ervas Chinesas / Biomarcadores Tipo de estudo: Diagnostic_studies / Guideline / Prognostic_studies Limite: Humans Idioma: Zh Revista: Zhongguo Zhong Yao Za Zhi Assunto da revista: FARMACOLOGIA / TERAPIAS COMPLEMENTARES Ano de publicação: 2017 Tipo de documento: Article País de afiliação: China