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A novel image-based high-throughput screening assay discovers therapeutic candidates for adult polyglucosan body disease.
Solmesky, Leonardo J; Khazanov, Netaly; Senderowitz, Hanoch; Wang, Peixiang; Minassian, Berge A; Ferreira, Igor M; Yue, Wyatt W; Lossos, Alexander; Weil, Miguel; Kakhlon, Or.
Afiliação
  • Solmesky LJ; Cell Screening Facility for Personalized Medicine, Department of Cell Research and Immunology, The George S. Wise Faculty of Life Sciences, Tel Aviv University, Tel Aviv, Israel.
  • Khazanov N; Department of Chemistry, Bar Ilan University, Ramat Gan, Israel.
  • Senderowitz H; Department of Chemistry, Bar Ilan University, Ramat Gan, Israel.
  • Wang P; Program in Genetics and Genome Biology, The Hospital for Sick Children, University of Toronto, Toronto, Canada.
  • Minassian BA; Program in Genetics and Genome Biology, The Hospital for Sick Children, University of Toronto, Toronto, Canada.
  • Ferreira IM; Department of Pediatrics, University of Texas Southwestern, Dallas, TX, U.S.A.
  • Yue WW; Structural Genomics Consortium, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, U.K.
  • Lossos A; Structural Genomics Consortium, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, U.K.
  • Weil M; Department of Neurology, Hadassah Medical Center, Hebrew University of Jerusalem Israel, Jerusalem, Israel.
  • Kakhlon O; Cell Screening Facility for Personalized Medicine, Department of Cell Research and Immunology, The Sagol School of Neurosciences, The George S. Wise Faculty of Life Sciences, Tel Aviv University, Tel Aviv, Israel ork@hadassah.org.il miguelw@tauex.tau.ac.il.
Biochem J ; 474(20): 3403-3420, 2017 09 28.
Article em En | MEDLINE | ID: mdl-28827282
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doença de Depósito de Glicogênio / Glicogênio Sintase / Fibroblastos / Doenças do Sistema Nervoso Tipo de estudo: Diagnostic_studies / Prognostic_studies / Screening_studies Limite: Adult / Female / Humans / Male Idioma: En Revista: Biochem J Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Israel
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doença de Depósito de Glicogênio / Glicogênio Sintase / Fibroblastos / Doenças do Sistema Nervoso Tipo de estudo: Diagnostic_studies / Prognostic_studies / Screening_studies Limite: Adult / Female / Humans / Male Idioma: En Revista: Biochem J Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Israel