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Positional cloning of quantitative trait nucleotides for blood pressure and cardiac QT-interval by targeted CRISPR/Cas9 editing of a novel long non-coding RNA.
Cheng, Xi; Waghulde, Harshal; Mell, Blair; Morgan, Eric E; Pruett-Miller, Shondra M; Joe, Bina.
Afiliação
  • Cheng X; Program in Physiological Genomics, Center for Hypertension and Personalized Medicine, Department of Physiology and Pharmacology, University of Toledo College of Medicine and Life Sciences, Toledo, OH, United States of America.
  • Waghulde H; Program in Physiological Genomics, Center for Hypertension and Personalized Medicine, Department of Physiology and Pharmacology, University of Toledo College of Medicine and Life Sciences, Toledo, OH, United States of America.
  • Mell B; Program in Physiological Genomics, Center for Hypertension and Personalized Medicine, Department of Physiology and Pharmacology, University of Toledo College of Medicine and Life Sciences, Toledo, OH, United States of America.
  • Morgan EE; Program in Physiological Genomics, Center for Hypertension and Personalized Medicine, Department of Physiology and Pharmacology, University of Toledo College of Medicine and Life Sciences, Toledo, OH, United States of America.
  • Pruett-Miller SM; Department of Radiology, University of Toledo Medical Center, Toledo, OH, United States of America.
  • Joe B; Department of Cell & Molecular Biology, Center for Advanced Genome Engineering, St. Jude Children's Research Hospital, Memphis, TN, United States of America.
PLoS Genet ; 13(8): e1006961, 2017 Aug.
Article em En | MEDLINE | ID: mdl-28827789

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pressão Sanguínea / RNA Longo não Codificante / Hipertensão / Proteínas do Tecido Nervoso Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: PLoS Genet Assunto da revista: GENETICA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pressão Sanguínea / RNA Longo não Codificante / Hipertensão / Proteínas do Tecido Nervoso Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: PLoS Genet Assunto da revista: GENETICA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Estados Unidos