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Selinexor (KPT-330) has antitumor activity against anaplastic thyroid carcinoma in vitro and in vivo and enhances sensitivity to doxorubicin.
Garg, Manoj; Kanojia, Deepika; Mayakonda, Anand; Ganesan, Trivadi S; Sadhanandhan, Bindhya; Suresh, Sidhanth; S, Sneha; Nagare, Rohit P; Said, Jonathan W; Doan, Ngan B; Ding, Ling-Wen; Baloglu, Erkan; Shacham, Sharon; Kauffman, Michael; Koeffler, H Phillip.
Afiliação
  • Garg M; Cancer Science Institute (CSI) of Singapore, National University of Singapore, Singapore, Singapore. manoj.garg@cancerinstitutewia.org.
  • Kanojia D; Department of Medical Oncology and Clinical Research, Cancer Institute (WIA), Adyar, Chennai, India. manoj.garg@cancerinstitutewia.org.
  • Mayakonda A; Cancer Science Institute (CSI) of Singapore, National University of Singapore, Singapore, Singapore.
  • Ganesan TS; Cancer Science Institute (CSI) of Singapore, National University of Singapore, Singapore, Singapore.
  • Sadhanandhan B; Department of Medical Oncology and Clinical Research, Cancer Institute (WIA), Adyar, Chennai, India.
  • Suresh S; Department of Medical Oncology and Clinical Research, Cancer Institute (WIA), Adyar, Chennai, India.
  • S S; Department of Medical Oncology and Clinical Research, Cancer Institute (WIA), Adyar, Chennai, India.
  • Nagare RP; Department of Medical Oncology and Clinical Research, Cancer Institute (WIA), Adyar, Chennai, India.
  • Said JW; Department of Medical Oncology and Clinical Research, Cancer Institute (WIA), Adyar, Chennai, India.
  • Doan NB; Department of Pathology and Laboratory Medicine, David Geffen School of Medicine, Los Angeles, CA, USA.
  • Ding LW; Department of Pathology and Laboratory Medicine, David Geffen School of Medicine, Los Angeles, CA, USA.
  • Baloglu E; Cancer Science Institute (CSI) of Singapore, National University of Singapore, Singapore, Singapore.
  • Shacham S; Karyopharm Therapeutics Inc, Newton, MA, 02459, USA.
  • Kauffman M; Karyopharm Therapeutics Inc, Newton, MA, 02459, USA.
  • Koeffler HP; Karyopharm Therapeutics Inc, Newton, MA, 02459, USA.
Sci Rep ; 7(1): 9749, 2017 08 29.
Article em En | MEDLINE | ID: mdl-28852098
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Triazóis / Neoplasias da Glândula Tireoide / Doxorrubicina / Carcinoma Anaplásico da Tireoide / Hidrazinas / Antineoplásicos Tipo de estudo: Diagnostic_studies Limite: Animals / Humans Idioma: En Revista: Sci Rep Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Singapura
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Triazóis / Neoplasias da Glândula Tireoide / Doxorrubicina / Carcinoma Anaplásico da Tireoide / Hidrazinas / Antineoplásicos Tipo de estudo: Diagnostic_studies Limite: Animals / Humans Idioma: En Revista: Sci Rep Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Singapura