Computational discovery and functional validation of novel fluoroquinolone resistance genes in public metagenomic data sets.

Boulund, Fredrik; Berglund, Fanny; Flach, Carl-Fredrik; Bengtsson-Palme, Johan; Marathe, Nachiket P; Larsson, D G Joakim; Kristiansson, Erik

Boulund, Fredrik; Berglund, Fanny; Flach, Carl-Fredrik; Bengtsson-Palme, Johan; Marathe, Nachiket P; Larsson, D G Joakim; Kristiansson, Erik.

Afiliação

Boulund F; Department of Mathematical sciences, Chalmers university of Technology and University of Gothenburg, Gothenburg, Sweden.
Berglund F; Centre for Antibiotic Resistance Research, University of Gothenburg, Gothenburg, Sweden.
Flach CF; Department of Mathematical sciences, Chalmers university of Technology and University of Gothenburg, Gothenburg, Sweden.
Bengtsson-Palme J; Centre for Antibiotic Resistance Research, University of Gothenburg, Gothenburg, Sweden.
Marathe NP; Centre for Antibiotic Resistance Research, University of Gothenburg, Gothenburg, Sweden.
Larsson DGJ; Department of Infectious Diseases, Institute of Biomedicine, University of Gothenburg, Gothenburg, Sweden.
Kristiansson E; Centre for Antibiotic Resistance Research, University of Gothenburg, Gothenburg, Sweden.

BMC Genomics ; 18(1): 682, 2017 Sep 02.

Article em En | MEDLINE | ID: mdl-28865446

Assuntos

Bases de Dados Genéticas; Farmacorresistência Bacteriana/genética; Fluoroquinolonas/farmacologia; Metagenômica; Humanos

Palavras-chave

Fluroquinolone resistance; Hidden Markov models; Horizontal gene transfer; Metagenomics; Qnr

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fluoroquinolonas / Farmacorresistência Bacteriana / Bases de Dados Genéticas / Metagenômica Tipo de estudo: Risk_factors_studies Limite: Humans Idioma: En Revista: BMC Genomics Assunto da revista: GENETICA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Suécia

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