Polyunsaturated fatty acids induce ovarian cancer cell death through ROS-dependent MAP kinase activation.

Tanaka, Aiko; Yamamoto, Akane; Murota, Kaeko; Tsujiuchi, Toshifumi; Iwamori, Masao; Fukushima, Nobuyuki

Tanaka, Aiko; Yamamoto, Akane; Murota, Kaeko; Tsujiuchi, Toshifumi; Iwamori, Masao; Fukushima, Nobuyuki.

Afiliação

Tanaka A; Division of Molecular Neurobiology, Department of Life Science, School of Science and Engineering, Kindai University, Higashiosaka, Japan.
Yamamoto A; Division of Molecular Neurobiology, Department of Life Science, School of Science and Engineering, Kindai University, Higashiosaka, Japan.
Murota K; Division of Food and Nutritional Chemistry, Department of Life Science, School of Science and Engineering, Kindai University, Higashiosaka, Japan.
Tsujiuchi T; Division of Molecular Oncology, Department of Life Science, School of Science and Engineering, Kindai University, Higashiosaka, Japan.
Iwamori M; Division of Biochemistry, Department of Life Science, School of Science and Engineering, Kindai University, Higashiosaka, Japan.
Fukushima N; Division of Molecular Neurobiology, Department of Life Science, School of Science and Engineering, Kindai University, Higashiosaka, Japan. Electronic address: nfukushima@life.kindai.ac.jp.

Biochem Biophys Res Commun ; 493(1): 468-473, 2017 11 04.

Article em En | MEDLINE | ID: mdl-28882592

Assuntos

Apoptose/efeitos dos fármacos; Ácidos Graxos Insaturados/administração & dosagem; Quinases de Proteína Quinase Ativadas por Mitógeno/metabolismo; Neoplasias Ovarianas/tratamento farmacológico; Neoplasias Ovarianas/metabolismo; Espécies Reativas de Oxigênio/metabolismo; Linhagem Celular Tumoral; Relação Dose-Resposta a Droga; Ativação Enzimática/efeitos dos fármacos; Feminino; Humanos; Sistema de Sinalização das MAP Quinases/efeitos dos fármacos

Palavras-chave

Apoptosis signal-regulating kinase 1; Docosahexaenoic acid; MAP kinase; Ovarian cancer cell death; Polyunsaturated fatty acid; Reactive oxygen species

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Ovarianas / Espécies Reativas de Oxigênio / Apoptose / Quinases de Proteína Quinase Ativadas por Mitógeno / Ácidos Graxos Insaturados Limite: Female / Humans Idioma: En Revista: Biochem Biophys Res Commun Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Japão

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