Differences in myocardial strain between pectus excavatum patients and healthy subjects assessed by cardiac MRI: a pilot study.
Eur Radiol
; 28(3): 1276-1284, 2018 Mar.
Article
em En
| MEDLINE
| ID: mdl-28894923
ABSTRACT
OBJECTIVES:
To evaluate differences in myocardial strain between pectus excavatum (PE) patients and healthy subjects (HS) assessed by cardiac MRI using the feature-tracking algorithm.METHODS:
Cardiac MRI was performed in 14 PE patients and 14 HS (95 male to female in each group; age 11-30 years) using a 3T scanner. Post-examination analysis included manual biventricular contouring with volumetry and ejection fraction measurement by two independent radiologists. Dedicated software was used for automated strain assessment.RESULTS:
In five of the PE patients, the right ventricular ejection fraction was slightly impaired (40-44 %). PE patients had a significantly higher left ventricular longitudinal strain (P=0.004), mid (P=0.035) and apical (P=0.001) circumferential strain as well as apical circumferential strain rate (P=0.001), mid right ventricular circumferential strain (P=0.008) and strain rate (P=0.035), and apical right ventricular circumferential strain (P=0.012) and strain rate (P=0.044) than HS. The right ventricular longitudinal strain and strain rate did not differ significantly between PE patients and HS.CONCLUSIONS:
Myocardial strain differs significantly between PE patients and HS. Higher myocardial strain in the mid and apical ventricles of PE patients indicates a compensation mechanism to enhance ventricular output against basal sternal compression. KEY POINTS ⢠The right ventricle is frequently affected by the pectus excavatum deformity. ⢠Cardiac MRI revealed differences in myocardial strain in pectus excavatum patients. ⢠Pectus excavatum patients exhibited higher strain in the mid/apical ventricles. ⢠A compensation mechanism to enhance ventricular output against sternal compression is possible.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Função Ventricular Direita
/
Disfunção Ventricular Direita
/
Imagem Cinética por Ressonância Magnética
/
Tórax em Funil
/
Ventrículos do Coração
/
Miocárdio
Tipo de estudo:
Etiology_studies
Limite:
Adolescent
/
Adult
/
Child
/
Female
/
Humans
/
Male
Idioma:
En
Revista:
Eur Radiol
Assunto da revista:
RADIOLOGIA
Ano de publicação:
2018
Tipo de documento:
Article
País de afiliação:
Alemanha