Quantification of N-phenyl-2-naphthylamine by gas chromatography and isotope-dilution mass spectrometry and its percutaneous absorption ex vivo under workplace conditions.

Marek, Eike Maximilian; Koslitz, Stephan; Weiss, Tobias; Fartasch, Manigé; Schlüter, Gerhard; Käfferlein, Heiko Udo; Brüning, Thomas

Marek, Eike Maximilian; Koslitz, Stephan; Weiss, Tobias; Fartasch, Manigé; Schlüter, Gerhard; Käfferlein, Heiko Udo; Brüning, Thomas.

Afiliação

Marek EM; Institute for Prevention and Occupational Medicine of the German Social Accident Insurance, Ruhr-University Bochum (IPA), Bürkle-de-la-Camp Platz 1, 44789, Bochum, Germany.
Koslitz S; Institute for Prevention and Occupational Medicine of the German Social Accident Insurance, Ruhr-University Bochum (IPA), Bürkle-de-la-Camp Platz 1, 44789, Bochum, Germany.
Weiss T; Institute for Prevention and Occupational Medicine of the German Social Accident Insurance, Ruhr-University Bochum (IPA), Bürkle-de-la-Camp Platz 1, 44789, Bochum, Germany.
Fartasch M; Institute for Prevention and Occupational Medicine of the German Social Accident Insurance, Ruhr-University Bochum (IPA), Bürkle-de-la-Camp Platz 1, 44789, Bochum, Germany.
Schlüter G; Institute for Prevention and Occupational Medicine of the German Social Accident Insurance, Ruhr-University Bochum (IPA), Bürkle-de-la-Camp Platz 1, 44789, Bochum, Germany.
Käfferlein HU; Institute for Prevention and Occupational Medicine of the German Social Accident Insurance, Ruhr-University Bochum (IPA), Bürkle-de-la-Camp Platz 1, 44789, Bochum, Germany. kaefferlein@ipa-dguv.de.
Brüning T; Institute for Prevention and Occupational Medicine of the German Social Accident Insurance, Ruhr-University Bochum (IPA), Bürkle-de-la-Camp Platz 1, 44789, Bochum, Germany.

Arch Toxicol ; 91(11): 3587-3596, 2017 Nov.

Article em En | MEDLINE | ID: mdl-28900691

Assuntos

2-Naftilamina/análogos & derivados; Cromatografia Gasosa-Espectrometria de Massas/métodos; Absorção Cutânea/efeitos dos fármacos; Espectrometria de Massas em Tandem/métodos; 2-Naftilamina/análise; 2-Naftilamina/farmacocinética; 2-Naftilamina/toxicidade; Animais; Alemanha; Humanos; Isótopos; Limite de Detecção; Cloreto de Metileno/farmacocinética; Exposição Ocupacional; Reprodutibilidade dos Testes; Suínos; Local de Trabalho

Palavras-chave

Franz diffusion cells; N-Phenyl-2-naphthylamine; N-Phenyl-ß-naphthylamine; Percutaneous penetration; Skin

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Absorção Cutânea / Espectrometria de Massas em Tandem / Cromatografia Gasosa-Espectrometria de Massas / 2-Naftilamina Limite: Animals / Humans País/Região como assunto: Europa Idioma: En Revista: Arch Toxicol Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Alemanha

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