Intermolecular interactions involving an acidic patch on immunoglobulin variable domain and the Î³2 constant region mediate crystalline inclusion body formation in the endoplasmic reticulum.

Hasegawa, Haruki; Geng, Mei; Ketchem, Randal R; Liu, Ling; Graham, Kevin; Jacobsen, Frederick

Hasegawa, Haruki; Geng, Mei; Ketchem, Randal R; Liu, Ling; Graham, Kevin; Jacobsen, Frederick.

Afiliação

Hasegawa H; Department of Therapeutic Discovery, Amgen Inc., South San Francisco, CA, USA.
Geng M; Department of Therapeutic Discovery, Amgen Inc., South San Francisco, CA, USA.
Ketchem RR; Department of Therapeutic Discovery, Amgen Inc., South San Francisco, CA, USA.
Liu L; Department of Therapeutic Discovery, Amgen Inc., Thousand Oaks, CA, USA.
Graham K; Department of Therapeutic Discovery, Amgen Inc., Thousand Oaks, CA, USA.
Jacobsen F; Department of Therapeutic Discovery, Amgen Inc., Thousand Oaks, CA, USA.

Cell Logist ; 7(3): e1361499, 2017.

Article em En | MEDLINE | ID: mdl-28944095

Palavras-chave

Russell body; acidic surface patch; crystalline body; endoplasmic reticulum; immunoglobulin; morular cell phenotype

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Idioma: En Revista: Cell Logist Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Estados Unidos

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