High Glucose Stimulates Mineralocorticoid Receptor Transcriptional Activity Through the Protein Kinase C ß Signaling.

Hayashi, Takeshi; Shibata, Hirotaka; Kurihara, Isao; Yokota, Kenichi; Mitsuishi, Yuko; Ohashi, Kennosuke; Murai-Takeda, Ayano; Jo, Rie; Ohyama, Takako; Sakamoto, Masaya; Tojo, Katsuyoshi; Tajima, Naoko; Utsunomiya, Kazunori; Itoh, Hiroshi

Hayashi, Takeshi; Shibata, Hirotaka; Kurihara, Isao; Yokota, Kenichi; Mitsuishi, Yuko; Ohashi, Kennosuke; Murai-Takeda, Ayano; Jo, Rie; Ohyama, Takako; Sakamoto, Masaya; Tojo, Katsuyoshi; Tajima, Naoko; Utsunomiya, Kazunori; Itoh, Hiroshi.

Afiliação

Hayashi T; Division of Endocrinology, Metabolism and Nephrology, Department of Internal Medicine, School of Medicine, Keio University.
Shibata H; Division of Diabetes, Metabolism and Endocrinology, Department of Internal Medicine, Jikei University School of Medicine.
Kurihara I; Department of Endocrinology, Metabolism, Rheumatology and Nephrology, Faculty of Medicine, Oita University.
Yokota K; Division of Endocrinology, Metabolism and Nephrology, Department of Internal Medicine, School of Medicine, Keio University.
Mitsuishi Y; Division of Endocrinology, Metabolism and Nephrology, Department of Internal Medicine, School of Medicine, Keio University.
Ohashi K; Division of Endocrinology, Metabolism and Nephrology, Department of Internal Medicine, School of Medicine, Keio University.
Murai-Takeda A; Division of Diabetes, Metabolism and Endocrinology, Department of Internal Medicine, Jikei University School of Medicine.
Jo R; Division of Endocrinology, Metabolism and Nephrology, Department of Internal Medicine, School of Medicine, Keio University.
Ohyama T; Division of Endocrinology, Metabolism and Nephrology, Department of Internal Medicine, School of Medicine, Keio University.
Sakamoto M; Division of Endocrinology, Metabolism and Nephrology, Department of Internal Medicine, School of Medicine, Keio University.
Tojo K; Division of Diabetes, Metabolism and Endocrinology, Department of Internal Medicine, Jikei University School of Medicine.
Tajima N; Division of Diabetes, Metabolism and Endocrinology, Department of Internal Medicine, Jikei University School of Medicine.
Utsunomiya K; Division of Diabetes, Metabolism and Endocrinology, Department of Internal Medicine, Jikei University School of Medicine.
Itoh H; Division of Diabetes, Metabolism and Endocrinology, Department of Internal Medicine, Jikei University School of Medicine.

Int Heart J ; 58(5): 794-802, 2017 Oct 21.

Article em En | MEDLINE | ID: mdl-28966330

Assuntos

Diabetes Mellitus Experimental; Regulação da Expressão Gênica; Glucose/administração & dosagem; Hipertensão/genética; Proteína Quinase C beta/genética; RNA/genética; Receptores de Mineralocorticoides/efeitos dos fármacos; Animais; Western Blotting; Células Cultivadas; Relação Dose-Resposta a Droga; Humanos; Hipertensão/tratamento farmacológico; Hipertensão/metabolismo; Camundongos; Camundongos Transgênicos; Proteína Quinase C beta/biossíntese; Coelhos; Reação em Cadeia da Polimerase em Tempo Real; Receptores de Mineralocorticoides/biossíntese; Receptores de Mineralocorticoides/genética; Transdução de Sinais/efeitos dos fármacos

Palavras-chave

Diabetes mellitus; Diabetic complication; Resistant hypertension

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: RNA / Regulação da Expressão Gênica / Receptores de Mineralocorticoides / Diabetes Mellitus Experimental / Proteína Quinase C beta / Glucose / Hipertensão Limite: Animals / Humans Idioma: En Revista: Int Heart J Assunto da revista: CARDIOLOGIA Ano de publicação: 2017 Tipo de documento: Article

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