Enantiomer resolution of nefopam hydrochloride, a novel analgesic: a study by liquid chromatography and circular dichroism spectroscopy.
J Pharm Pharmacol
; 40(1): 48-50, 1988 Jan.
Article
em En
| MEDLINE
| ID: mdl-2896773
ABSTRACT
Nefopam, a potent analgesic, has been completely resolved into enantiomers on a preparative scale by low-pressure liquid chromatography on swollen, microcrystalline triacetylcellulose. The enantiomerically pure hydrochlorides were prepared from the base, and the circular dichroism spectra of the free base and the hydrochloride are reported.
Buscar no Google
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Oxazocinas
/
Analgésicos
/
Nefopam
Idioma:
En
Revista:
J Pharm Pharmacol
Ano de publicação:
1988
Tipo de documento:
Article
País de afiliação:
Suécia