Neuroblastoma Metastases: Leveraging the Avian Neural Crest.

Zheng, Tina; Ménard, Marie; Weiss, William A

Zheng, Tina; Ménard, Marie; Weiss, William A.

Afiliação

Zheng T; Departments of Neurology, Pediatrics, and Neurosurgery, Brain Tumor Research Center, University of California, San Francisco, CA 94158, USA; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, CA 94158, USA.
Ménard M; Departments of Neurology, Pediatrics, and Neurosurgery, Brain Tumor Research Center, University of California, San Francisco, CA 94158, USA; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, CA 94158, USA.
Weiss WA; Departments of Neurology, Pediatrics, and Neurosurgery, Brain Tumor Research Center, University of California, San Francisco, CA 94158, USA; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, CA 94158, USA. Electronic address: waweiss@gmail.com.

Cancer Cell ; 32(4): 395-397, 2017 10 09.

Article em En | MEDLINE | ID: mdl-29017050

ABSTRACT

ABSTRACT

Neuroblastoma, an embryonal cancer of neural crest origin, shows metastases frequently at diagnosis. In this issue of Cancer Cell, Delloye-Bourgeois and colleagues demonstrate that neuroblastoma cell lines and patient-derived xenografts engraft and adopt a metastatic program in chick embryos. They identify Sema3C as a candidate switch that regulates metastatic spread.

Assuntos

Crista Neural; Neuroblastoma; Animais; Embrião de Galinha; Humanos; Microambiente Tumoral

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Crista Neural / Neuroblastoma Limite: Animals / Humans Idioma: En Revista: Cancer Cell Assunto da revista: NEOPLASIAS Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Estados Unidos

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