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The DNA Inflammasome in Human Myeloid Cells Is Initiated by a STING-Cell Death Program Upstream of NLRP3.
Gaidt, Moritz M; Ebert, Thomas S; Chauhan, Dhruv; Ramshorn, Katharina; Pinci, Francesca; Zuber, Sarah; O'Duill, Fionan; Schmid-Burgk, Jonathan L; Hoss, Florian; Buhmann, Raymund; Wittmann, Georg; Latz, Eicke; Subklewe, Marion; Hornung, Veit.
Afiliação
  • Gaidt MM; Gene Center and Department of Biochemistry, Ludwig-Maximilians-Universität München, 81377 Munich, Germany.
  • Ebert TS; Gene Center and Department of Biochemistry, Ludwig-Maximilians-Universität München, 81377 Munich, Germany.
  • Chauhan D; Gene Center and Department of Biochemistry, Ludwig-Maximilians-Universität München, 81377 Munich, Germany.
  • Ramshorn K; Gene Center and Department of Biochemistry, Ludwig-Maximilians-Universität München, 81377 Munich, Germany.
  • Pinci F; Gene Center and Department of Biochemistry, Ludwig-Maximilians-Universität München, 81377 Munich, Germany.
  • Zuber S; Gene Center and Department of Biochemistry, Ludwig-Maximilians-Universität München, 81377 Munich, Germany.
  • O'Duill F; Gene Center and Department of Biochemistry, Ludwig-Maximilians-Universität München, 81377 Munich, Germany.
  • Schmid-Burgk JL; Gene Center and Department of Biochemistry, Ludwig-Maximilians-Universität München, 81377 Munich, Germany.
  • Hoss F; Institute of Innate Immunity, University Hospital, University of Bonn, 53127 Bonn, Germany.
  • Buhmann R; Department of Transfusion Medicine, University Hospital, Ludwig-Maximilians-Universität München, 81377 Munich, Germany.
  • Wittmann G; Department of Transfusion Medicine, University Hospital, Ludwig-Maximilians-Universität München, 81377 Munich, Germany.
  • Latz E; Institute of Innate Immunity, University Hospital, University of Bonn, 53127 Bonn, Germany; Department of Infectious Diseases and Immunology, University of Massachusetts Medical School, Worcester, MA 01655, USA.
  • Subklewe M; Laboratory for Translational Cancer Immunology, Gene Center, Ludwig-Maximilians-Universität München, 81377 Munich, Germany; Department of Medicine III, University Hospital, Ludwig-Maximilians-Universität München, 81377 Munich, Germany.
  • Hornung V; Gene Center and Department of Biochemistry, Ludwig-Maximilians-Universität München, 81377 Munich, Germany; Center for Integrated Protein Science (CIPSM), Ludwig-Maximilians-Universität München, 81377 Munich, Germany. Electronic address: hornung@genzentrum.lmu.de.
Cell ; 171(5): 1110-1124.e18, 2017 Nov 16.
Article em En | MEDLINE | ID: mdl-29033128
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Monócitos / Morte Celular / Inflamassomos / Proteína 3 que Contém Domínio de Pirina da Família NLR Limite: Humans Idioma: En Revista: Cell Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Alemanha
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Monócitos / Morte Celular / Inflamassomos / Proteína 3 que Contém Domínio de Pirina da Família NLR Limite: Humans Idioma: En Revista: Cell Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Alemanha